RNF25

Description		ring finger protein 25
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytosolic Ribosome
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding NF-kappaB Binding Ubiquitin Protein Ligase Activity
	Biological Process	Translational Elongation Translational Termination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity Rescue Of Stalled Ribosome Protein K6-linked Ubiquitination Protein-RNA Covalent Cross-linking Repair
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072)
Novel Interacting Genes		11 novel interacting genes: CHPF KCTD21 MEOX2 RELA TRIM27 UBE2D1 UBE2D2 UBE2D4 UBE2E2 UBE2L6 UBE2U
Interacting Genes		11 interacting genes: CHPF KCTD21 MEOX2 RELA TRIM27 UBE2D1 UBE2D2 UBE2D4 UBE2E2 UBE2L6 UBE2U
Entrez ID		64320
HPRD ID		09737
Ensembl ID		ENSG00000163481
Uniprot IDs		Q96BH1
PDB IDs		2DAY 2DMF 5D1K 5D1L 5D1M
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Post-translational Protein Modification Ubiquitin-protein Transferase Activity Protein Metabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Protein Modification Process Transferase Activity Proteolysis Involved In Protein Catabolic Process ISG15 Transferase Activity ISG15-protein Conjugation Protein K63-linked Ubiquitination Macromolecule Metabolic Process Proteolysis Catabolic Process Ubiquitin-like Protein Transferase Activity Protein K11-linked Ubiquitination ATP Binding NF-kappaB P50/p65 Complex Ubiquitin Protein Ligase Activity Positive Regulation Of Schwann Cell Differentiation Response To Cobalamin N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase Activity Toll-like Receptor TLR6:TLR2 Signaling Pathway Regulation Of Schwann Cell Differentiation NF-kappaB Complex Prolactin Signaling Pathway Nucleotide Binding Somite Specification Postsynapse To Nucleus Signaling Pathway Histone Deacetylase Binding Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase Activity HULC Complex
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