LRRC4

Description		leucine rich repeat containing 4
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GO Annotations	Cellular Component	Plasma Membrane Membrane Dendritic Spine Neuron Spine Synapse Postsynaptic Membrane Excitatory Synapse Schaffer Collateral - CA1 Synapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Modulation Of Chemical Synaptic Transmission Synapse Organization Postsynaptic Density Protein 95 Clustering Synaptic Membrane Adhesion Excitatory Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Alcohol consumption (drinks per week) ( 30643258) Brain morphology (MOSTest) ( 32665545) Fruit consumption ( 32066663) Risk-taking tendency (4-domain principal component model) ( 30643258) Subcortical volume (MOSTest) ( 32665545)
Novel Interacting Genes		5 novel interacting genes: LCOR MAPK1 MAPK3 SNCA SPP1
Interacting Genes		5 interacting genes: LCOR MAPK1 MAPK3 SNCA SPP1
Entrez ID		64101
HPRD ID		10060
Ensembl ID		ENSG00000128594
Uniprot IDs		Q9HBW1
PDB IDs		2DL9 3ZYI
Enriched GO Terms of Interacting Partners?		Interleukin-34-mediated Signaling Pathway Response To Lipid Caveolin-mediated Endocytosis Regulation Of Golgi Inheritance Positive Regulation Of Macrophage Proliferation Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation Response To Cytokine Response To Peptide Positive Regulation Of Inflammatory Response Regulation Of Golgi Organization MAP Kinase Activity Pseudopodium Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Neuroinflammatory Response Animal Organ Formation Face Development Stress-activated MAPK Cascade ERBB2 Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of Macrophage Migration Neural Crest Cell Development Lung Morphogenesis Regulation Of Macrophage Chemotaxis Thyroid Gland Development Astrocyte Differentiation Insulin-like Growth Factor Receptor Signaling Pathway Stem Cell Development Regulation Of Stress-activated MAPK Cascade Regulation Of Stress-activated Protein Kinase Signaling Cascade Lipopolysaccharide-mediated Signaling Pathway Endoplasmic Reticulum Lumen Response To Exogenous DsRNA Regulation Of Neuroinflammatory Response Response To Lipopolysaccharide Response To Growth Factor Response To Molecule Of Bacterial Origin Response To DsRNA Regulation Of Macrophage Migration Phosphotyrosine Residue Binding Thymus Development Regulation Of Granulocyte Chemotaxis Phosphatase Binding Response To Epidermal Growth Factor
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