ZNF335

Description		zinc finger protein 335
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Histone Methyltransferase Complex
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Histone Methyltransferase Binding
	Biological Process	In Utero Embryonic Development Positive Regulation Of Neuroblast Proliferation Brain Development Positive Regulation Of Cell Population Proliferation Regulation Of Gene Expression Cerebral Cortex Neuron Differentiation Epigenetic Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Neuron Projection Morphogenesis Brain Morphogenesis Positive Regulation Of Lymphocyte Proliferation Regulation Of Neurogenesis Positive Regulation Of Neurogenesis
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Abdominal aortic aneurysm ( 27899403) C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809) Celiac disease ( 25920553) Coronary artery disease ( 29212778 33020668) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Myocardial infarction ( 33532862)
Novel Interacting Genes		6 novel interacting genes: CCAR2 CDK4 CDK6 HSPB2 NCOA6 USP7
Interacting Genes		6 interacting genes: CCAR2 CDK4 CDK6 HSPB2 NCOA6 USP7
Entrez ID		63925
HPRD ID		11709
Ensembl ID		ENSG00000198026
Uniprot IDs		Q8IW09 Q9H4Z2
PDB IDs
Enriched GO Terms of Interacting Partners?		Cyclin Binding Cyclin-dependent Protein Serine/threonine Kinase Activity DNA Damage Response Cyclin-dependent Protein Kinase Holoenzyme Complex Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Fibroblast Proliferation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cyclin D2-CDK6 Complex Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Fibroblast Proliferation Cyclin D1-CDK4 Complex Regulation Of G2/M Transition Of Mitotic Cell Cycle Cyclin D3-CDK4 Complex Cyclin D3-CDK6 Complex Cyclin D1-CDK6 Complex FBXO Family Protein Binding Unfolded Protein Binding Regulation Of Circadian Rhythm Negative Regulation Of Protein Catabolic Process DBIRD Complex Regulation Of DNA-templated Transcription Cyclin D2-CDK4 Complex Regulation Of RNA Biosynthetic Process Response To Stress Cellular Response To Stress Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteolysis Symbiont-mediated Disruption Of Host Cell PML Body Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Process Cell Cycle Phase Transition Somatic Muscle Development Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of DNA Damage Checkpoint Cellular Response To Ionomycin Gliogenesis Negative Regulation Of Monocyte Differentiation Cell Dedifferentiation Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Proteasomal Protein Catabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Establishment Of Protein Localization To Chromosome Regulation Of Retrograde Transport, Endosome To Golgi Nucleus
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