CCL23

Description		C-C motif chemokine ligand 23
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity Heparin Binding CCR1 Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Monocyte Chemotaxis Intracellular Calcium Ion Homeostasis Chemotaxis Inflammatory Response Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Negative Regulation Of Cell Population Proliferation Positive Regulation Of Cell Migration Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Pulmonary function ( 23932459)
Novel Interacting Genes		2 novel interacting genes: CCL21 CCR1
Interacting Genes		2 interacting genes: CCL21 CCR1
Entrez ID		6368
HPRD ID		03930
Ensembl ID		ENSG00000274736
Uniprot IDs		P55773
PDB IDs		1G91
Enriched GO Terms of Interacting Partners?		Dendritic Cell Chemotaxis Dendritic Cell Migration Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of Mononuclear Cell Migration Mononuclear Cell Migration Positive Regulation Of Leukocyte Migration Chemokine-mediated Signaling Pathway Myeloid Leukocyte Migration Positive Regulation Of Chemotaxis Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of ERK1 And ERK2 Cascade Dendritic Cell Dendrite Assembly Negative Regulation Of Dendritic Cell Dendrite Assembly Regulation Of Leukocyte Migration Cell Chemotaxis Regulation Of Chemotaxis Leukocyte Migration Chemokine (C-C Motif) Ligand 5 Binding Chemokine (C-C Motif) Ligand 7 Binding Calcium Ion Transport Positive Regulation Of Myeloid Dendritic Cell Chemotaxis Mesangial Cell-matrix Adhesion CCR7 Chemokine Receptor Binding CCL21-activated CCR7 Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Chemotaxis Regulation Of Dendritic Cell Dendrite Assembly Locomotion Negative Regulation Of Leukocyte Tethering Or Rolling Chemokine (C-C Motif) Ligand 21 Signaling Pathway Cytokine-mediated Signaling Pathway Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Cellular Response To Cytokine Stimulus Positive Regulation Of MAPK Cascade Positive Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Cell Migration Response To Peptide Metal Ion Transport Inflammatory Response Positive Regulation Of Cell Motility Response To Cytokine Positive Regulation Of Dendritic Cell Chemotaxis Negative Regulation Of Dendritic Cell Apoptotic Process Chemokine Receptor Binding Establishment Of T Cell Polarity Negative Regulation Of Cellular Extravasation Positive Regulation Of Locomotion Cell-cell Signaling Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
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