SLC5A7

Description		solute carrier family 5 member 7
Image
GO Annotations	Cellular Component	Endosome Plasma Membrane Membrane Axon Dendrite Synaptic Vesicle Membrane Cytoplasmic Vesicle Neuromuscular Junction Early Endosome Membrane Presynaptic Membrane Cell Projection Neuronal Cell Body Perikaryon Synapse Presynapse
	Molecular Function	Choline:sodium Symporter Activity Choline Transmembrane Transporter Activity Symporter Activity Transmembrane Transporter Activity Choline Binding
	Biological Process	In Utero Embryonic Development Monoatomic Ion Transport Sodium Ion Transport Neurotransmitter Transport Synaptic Transmission, Cholinergic Neuromuscular Synaptic Transmission Acetylcholine Biosynthetic Process Choline Transport Transmembrane Transport
Pathways		Acetylcholine Neurotransmitter Release Cycle Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) SLC-mediated bile acid transport
Drugs
Diseases
GWAS
Novel Interacting Genes		2 novel interacting genes: PAWR SNCA
Interacting Genes		2 interacting genes: PAWR SNCA
Entrez ID		60482
HPRD ID		12294
Ensembl ID		ENSG00000115665
Uniprot IDs		B2RCU2 B4DUU7 Q2T9H3 Q9GZV3
PDB IDs		8J74 8J75 8J76 8J77 8ZQO 8ZQP 8ZQQ 8ZQR 9BFI 9BFJ 9BFK 9BIM
Enriched GO Terms of Interacting Partners?		Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Amyloid Precursor Protein Biosynthetic Process Enzyme Binding Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Actin Binding Actin Cytoskeleton Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Serotonin Uptake Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Programmed Cell Death Positive Regulation Of Apoptotic Process Supramolecular Fiber Organization Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding Regulation Of Chaperone-mediated Autophagy Response To Iron(II) Ion Dopamine Biosynthetic Process Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Regulation Of Acyl-CoA Biosynthetic Process Supramolecular Fiber Leucine Zipper Domain Binding Catecholamine Uptake Dopamine Uptake Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Cell Activation SNARE Complex Assembly Cellular Response To Epinephrine Stimulus Positive Regulation Of Receptor Recycling Positive Regulation Of Glycoprotein Metabolic Process Negative Regulation Of B Cell Proliferation Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Cellular Senescence Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Neurotransmitter Secretion Regulation Of SNARE Complex Assembly Regulation Of Hydrogen Peroxide Metabolic Process
Tagcloud ?