PTPRE

Description		protein tyrosine phosphatase receptor type E
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane
	Molecular Function	Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Identical Protein Binding
	Biological Process	Protein Dephosphorylation Signal Transduction Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Regulation Of Mast Cell Activation Negative Regulation Of Insulin Receptor Signaling Pathway
Pathways
Drugs		Alendronic acid Tiludronic acid
Diseases
GWAS		Response to amphetamines ( 22952603) Select biomarker traits ( 17903293) Triglyceride levels x loop diuretics use interaction ( 31806883)
Novel Interacting Genes		12 novel interacting genes: FGFR2 FYN GRB2 KCNA5 KCNB1 MAPK1 MAPK3 PTPRD PTPRS SRC TUBB4B YES1
Interacting Genes		12 interacting genes: FGFR2 FYN GRB2 KCNA5 KCNB1 MAPK1 MAPK3 PTPRD PTPRS SRC TUBB4B YES1
Entrez ID		5791
HPRD ID		02956
Ensembl ID		ENSG00000132334
Uniprot IDs		A8K2Z9 P23469 Q96P81
PDB IDs		2JJD 6D3F 6D4D 6D4F
Enriched GO Terms of Interacting Partners?		Enzyme-linked Receptor Protein Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Response To Growth Factor Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response T Cell Costimulation Phosphotyrosine Residue Binding Cellular Response To Transforming Growth Factor Beta Stimulus Epidermal Growth Factor Receptor Signaling Pathway Response To Transforming Growth Factor Beta Caveola ERBB Signaling Pathway Negative Regulation Of Immune Response Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Regulation Of Defense Response Cellular Response To Platelet-derived Growth Factor Stimulus Modulation Of Chemical Synaptic Transmission Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Immune Response-activating Cell Surface Receptor Signaling Pathway ERBB2 Signaling Pathway Protein Kinase Activity Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Negative Regulation Of Immune System Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Ephrin Receptor Binding Regulation Of Multicellular Organismal Process Negative Regulation Of Inflammatory Response To Antigenic Stimulus Interleukin-34-mediated Signaling Pathway Protein Tyrosine Kinase Activity Insulin-like Growth Factor Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Kinase Activity Regulation Of Immune System Process Transmembrane Transporter Binding Signal Transduction Protein Phosphorylation Immune Response-activating Signaling Pathway Regulation Of Golgi Inheritance Non-membrane Spanning Protein Tyrosine Kinase Activity Plasma Membrane Phosphorylation Regulation Of Leukocyte Cell-cell Adhesion Regulation Of T Cell Activation Immune Effector Process Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Signaling Receptor Binding
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