GBA3

Description		glucosylceramidase beta 3 (gene/pseudogene)
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GO Annotations	Cellular Component	Cytoplasm Cytosol Membrane Catalytic Complex
	Molecular Function	Galactosylceramidase Activity Glucosylceramidase Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Beta-galactosidase Activity Protein Binding Beta-glucosidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds Glycosylceramidase Activity
	Biological Process	Carbohydrate Metabolic Process Lipid Metabolic Process Glucosylceramide Catabolic Process Galactosylceramide Catabolic Process Oligosaccharide Catabolic Process Carbohydrate Catabolic Process Glycoside Catabolic Process Glycosylceramide Catabolic Process Glycosphingolipid Catabolic Process Protein Stabilization Beta-glucoside Catabolic Process Positive Regulation Of Exo-alpha-sialidase Activity
Pathways		Glycosphingolipid catabolism
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 30946743) Anti-saccade response ( 29064472) Fasting glucose ( 33381925) Manganese levels ( 26025379) Metabolite levels ( 23823483) Peak cortisol response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Rosacea symptom severity ( 29771307) Serum metabolite levels ( 23093944 33031748) Tourette's syndrome or obsessive-compulsive disorder ( 25158072) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) White matter lesion progression (adjusted for white matter lesion burden at baseline) ( 26451028)
Interacting Genes		2 interacting genes: PRKCSH TNS2
Entrez ID		57733
HPRD ID		09428
Ensembl ID		ENSG00000249948
Uniprot IDs		A8K9N1 B7Z536 Q9H227
PDB IDs		2E9L 2E9M 2JFE 2ZOX 3VKK
Enriched GO Terms of Interacting Partners?		Glucosidase II Complex
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