TNRC6C

Description		trinucleotide repeat containing adaptor 6C
Image
GO Annotations	Cellular Component	P-body Nucleoplasm Cytosol
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding
	Biological Process	Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Pathways		Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway Post-transcriptional silencing by small RNAs TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Nuclear events stimulated by ALK signaling in cancer Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH1 mRNA translation by microRNAs Regulation of NPAS4 mRNA translation Regulation of MITF-M-dependent genes involved in apoptosis TGFBR3 expression Regulation of PD-L1(CD274) translation
Drugs
Diseases
GWAS		Normal facial asymmetry (angle of deformation score) ( 30631343) Refractive error ( 32231278) Serum uric acid levels ( 29559957) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Uterine fibroid number (single vs multiple) ( 30196971)
Novel Interacting Genes		2 novel interacting genes: RPTOR UBC
Interacting Genes		2 interacting genes: RPTOR UBC
Entrez ID		57690
HPRD ID		10026
Ensembl ID		ENSG00000078687
Uniprot IDs		Q9HCJ0
PDB IDs		2DKL 2X04 3KTP 7RUQ
Enriched GO Terms of Interacting Partners?		Regulation Of NADP Metabolic Process Positive Regulation Of Pentose-phosphate Shunt Positive Regulation Of Odontoblast Differentiation TORC1 Complex Positive Regulation Of Neuroepithelial Cell Differentiation Regulation Of Pentose-phosphate Shunt Protein Tag Activity Positive Regulation Of Transcription By RNA Polymerase III Enzyme-substrate Adaptor Activity Response To L-leucine Cellular Response To L-leucine Regulation Of Odontoblast Differentiation Positive Regulation Of Glycolytic Process Serine/threonine Protein Kinase Complex Protein Serine/threonine Kinase Inhibitor Activity Positive Regulation Of Osteoclast Differentiation Regulation Of Transcription By RNA Polymerase III Endocytic Vesicle Membrane Protein Localization To Lysosome Cellular Response To Glucose Stimulus Positive Regulation Of TOR Signaling Positive Regulation Of Epithelial Cell Differentiation 14-3-3 Protein Binding Regulation Of Carbohydrate Catabolic Process Response To Osmotic Stress Cellular Response To Osmotic Stress Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Regulation Of Cell Size Negative Regulation Of Translational Initiation Social Behavior Regulation Of Osteoclast Differentiation Intracellular Glucose Homeostasis TOR Signaling Positive Regulation Of Translational Initiation Protein Kinase Activator Activity Regulation Of Amide Metabolic Process Positive Regulation Of Myeloid Leukocyte Differentiation Cellular Response To Amino Acid Stimulus Regulation Of Purine Nucleotide Metabolic Process TORC1 Signaling Positive Regulation Of ATP Metabolic Process Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Protein Localization To Vacuole Positive Regulation Of Endothelial Cell Proliferation Cytoplasmic Stress Granule Positive Regulation Of Mitotic Cell Cycle Phase Transition
Tagcloud ?