UVSSA

Description		UV stimulated scaffold protein A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Site Of DNA Damage
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Zinc Ion Binding Metal Ion Binding Chromatin-protein Adaptor Activity RNA Polymerase Inhibitor Activity
	Biological Process	DNA Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization DNA Damage Response Response To UV Protein Ubiquitination
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Chronotype ( 30696823)
Novel Interacting Genes		8 novel interacting genes: ERCC8 KPNA3 MAGEA4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1
Interacting Genes		8 interacting genes: ERCC8 KPNA3 MAGEA4 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1
Entrez ID		57654
HPRD ID		17216
Ensembl ID		ENSG00000163945
Uniprot IDs		A0A7I2V4K1 Q2YD98
PDB IDs		5XV8 7OO3 7OOP 7OPC 7OPD 8B3D 8B3G 8QH5 9BZ0 9ER2 9FD2
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Ubiquitination Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification Macromolecule Catabolic Process Proteolysis Protein Autoubiquitination Protein Modification Process Catabolic Process Protein K6-linked Ubiquitination Protein K11-linked Ubiquitination ATP Binding Protein Monoubiquitination Nucleus Regulation Of Transcription-coupled Nucleotide-excision Repair Nucleotide Binding Negative Regulation Of BMP Signaling Pathway Ubiquitin Protein Ligase Activity Transferase Activity Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of BMP Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Viral Penetration Into Host Nucleus ISG15 Transferase Activity Protein Catabolic Process Nucleoplasm Nucleotide-excision Repair Complex Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway ISG15-protein Conjugation Intracellular Transport Of Virus Protein-containing Complex Host Cell NLS-dependent Protein Nuclear Import Complex Double-strand Break Repair Via Classical Nonhomologous End Joining Single Strand Break Repair Transcription-coupled Nucleotide-excision Repair Protein K29-linked Ubiquitination Cul4A-RING E3 Ubiquitin Ligase Complex Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Protein K27-linked Ubiquitination
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