JCAD

Description		junctional cadherin 5 associated
Image		No pdb structure
GO Annotations	Cellular Component	Cell-cell Junction Adherens Junction Cell Junction Ruffle Membrane Perinuclear Region Of Cytoplasm Anchoring Junction
	Molecular Function
	Biological Process	Cell Adhesion Positive Regulation Of MAPK Cascade Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Positive Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Sprouting Angiogenesis
Pathways
Drugs
Diseases
GWAS		Alcohol use disorder (total score) ( 30336701) Coronary artery disease ( 33020668) Intraocular pressure ( 29617998) Myocardial infarction ( 33532862)
Novel Interacting Genes		4 novel interacting genes: DYRK1A IL2RA MAP3K8 YAP1
Interacting Genes		4 interacting genes: DYRK1A IL2RA MAP3K8 YAP1
Entrez ID		57608
HPRD ID		13864
Ensembl ID		ENSG00000165757
Uniprot IDs		Q9P266
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Lymphocyte Activation Protein Serine/threonine Kinase Activity Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Activation Positive Regulation Of Cell-cell Adhesion Positive Regulation Of T Cell Activation Phosphate-containing Compound Metabolic Process Phosphorylation Positive Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Inflammatory Response Regulation Of T Cell Activation Protein Phosphorylation Regulation Of Leukocyte Cell-cell Adhesion Protein Serine Kinase Activity RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Transcription Coactivator Activity Negative Regulation Of Microtubule Polymerization Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Heterochromatin Formation Regulation Of Neurofibrillary Tangle Assembly Neurofilament Splicing Factor Binding Regulation Of Heterochromatin Formation Histone H3T45 Kinase Activity Activated T Cell Proliferation Regulation Of T Cell Homeostatic Proliferation Interleukin-2 Receptor Complex Cytokine-mediated Signaling Pathway Interleukin-2 Binding Interleukin-2-mediated Signaling Pathway Interleukin-2 Receptor Activity Activation-induced Cell Death Of T Cells Regulation Of T Cell Tolerance Induction Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Branch Elongation Of An Epithelium Lateral Mesoderm Development Intestinal Epithelial Cell Development Bud Elongation Involved In Lung Branching Regulation Of Nephron Tubule Epithelial Cell Differentiation TEAD-YAP Complex Notochord Development Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Female Germ Cell Nucleus Cardiac Muscle Tissue Regeneration Enterocyte Differentiation Paraxial Mesoderm Development Intestinal Epithelial Cell Differentiation Columnar/cuboidal Epithelial Cell Development Interleukin-6-mediated Signaling Pathway MAP Kinase Kinase Kinase Activity
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