ARHGAP31

Description		Rho GTPase activating protein 31
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Focal Adhesion Lamellipodium Cell Projection Anchoring Junction
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding
	Biological Process	Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOU GTPase cycle
Drugs
Diseases
GWAS		Celiac disease ( 22057235 30572963) Schizophrenia ( 23894747) Systemic sclerosis ( 31672989)
Novel Interacting Genes		7 novel interacting genes: CDC42 ITSN1 RAC1 RHOA SMURF1 TGFBR1 TLN1
Interacting Genes		7 interacting genes: CDC42 ITSN1 RAC1 RHOA SMURF1 TGFBR1 TLN1
Entrez ID		57514
HPRD ID		16697
Ensembl ID		ENSG00000031081
Uniprot IDs		A0A8S0MHV1 Q2M1Z3
PDB IDs
Enriched GO Terms of Interacting Partners?		Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Stress Fiber Assembly Membrane Invagination Non-canonical Wnt Signaling Pathway Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Stress Fiber Assembly Cell-cell Junction Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Organization Regulation Of Cell-substrate Adhesion Regulation Of Cellular Component Organization Regulation Of Plasma Membrane Bounded Cell Projection Organization Regulation Of Cell Projection Organization Wnt Signaling Pathway Regulation Of Actin Filament Organization Regulation Of Focal Adhesion Assembly G Protein Activity Regulation Of Cell-substrate Junction Organization Regulation Of Modification Of Postsynaptic Actin Cytoskeleton G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Synapse Organization Regulation Of Actin Cytoskeleton Organization Ruffle Membrane Actin Cytoskeleton Organization Thioesterase Binding Positive Regulation Of Cell Projection Organization Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Actin Filament-based Process Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Focal Adhesion Regulation Of Cell-matrix Adhesion Regulation Of Modification Of Postsynaptic Structure Cell Surface Receptor Signaling Pathway Cell Junction Organization I-SMAD Binding Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Postsynapse Organization Supramolecular Fiber Organization Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Component Biogenesis Regulation Of Modification Of Synaptic Structure Establishment Or Maintenance Of Cell Polarity Positive Regulation Of Cell Growth Regulation Of Cytoskeleton Organization GTP-dependent Protein Binding Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Positive Regulation Of Cell Migration
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