DSCAML1

Description		DS cell adhesion molecule like 1
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Cell Surface Membrane Axon Synapse
	Molecular Function	Protein Homodimerization Activity Cell-cell Adhesion Mediator Activity
	Biological Process	Cell Fate Determination Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Nervous System Development Axonogenesis Axon Guidance Central Nervous System Development Brain Development Dorsal/ventral Pattern Formation Embryonic Skeletal System Morphogenesis Dendrite Self-avoidance
Pathways		DSCAM interactions
Drugs
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Lipoprotein (a) - cholesterol levels ( 25575512) Menarche (age at onset) ( 23599027) Myopia ( 27182965) Putamen volume ( 29147026) Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Triglyceride levels ( 28548082) Triglycerides ( 19074352 30275531) Very low density lipoprotein cholesterol levels ( 28548082)
Novel Interacting Genes		4 novel interacting genes: DYRK1A MAGI2 MAGI3 PLCL2
Interacting Genes		4 interacting genes: DYRK1A MAGI2 MAGI3 PLCL2
Entrez ID		57453
HPRD ID		10921
Ensembl ID		ENSG00000177103
Uniprot IDs		A0A384DVL8 Q8TD84
PDB IDs		1VA9
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Signal Transduction RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Phosphate-containing Compound Metabolic Process Negative Regulation Of Cell Communication Negative Regulation Of Heterochromatin Formation Regulation Of Neurofibrillary Tangle Assembly Neurofilament Negative Regulation Of Signaling Splicing Factor Binding Regulation Of Heterochromatin Formation Histone H3T45 Kinase Activity Podocyte Development Cell-cell Junction Beta-1 Adrenergic Receptor Binding Slit Diaphragm Type II Activin Receptor Binding Bicellular Tight Junction B Cell Proliferation Involved In Immune Response B-1a B Cell Differentiation Negative Regulation Of B Cell Receptor Signaling Pathway B-1 B Cell Differentiation GMP Kinase Activity GDP Metabolic Process Inositol 1,4,5 Trisphosphate Binding Negative Regulation Of Microtubule Polymerization Nerve Growth Factor Signaling Pathway Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Activin Receptor Signaling Pathway GABA Receptor Binding Dendrite Intracellular Signal Transduction Tau-protein Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Chromatin Organization Nervous System Development Negative Regulation Of RNA Splicing Regulation Of Inclusion Body Assembly Neurotrophin Signaling Pathway Positive Regulation Of Receptor Internalization SMAD Protein Signal Transduction Regulation Of Activin Receptor Signaling Pathway Regulation Of B Cell Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Gamma-aminobutyric Acid Signaling Pathway Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity GMP Metabolic Process Clathrin-dependent Endocytosis Signaling Receptor Complex Adaptor Activity Wnt Signaling Pathway, Planar Cell Polarity Pathway
Tagcloud ?