NDRG2

Description		NDRG family member 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Cytosol Growth Cone Cell Projection Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding
	Biological Process	Negative Regulation Of Cytokine Production Signal Transduction Nervous System Development Regulation Of Vascular Endothelial Growth Factor Production Wnt Signaling Pathway Substantia Nigra Development Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Platelet-derived Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Proliferation
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Drugs
Diseases
GWAS		Heart rate response to exercise ( 29769521) Hip circumference adjusted for BMI ( 28552196) Resting heart rate ( 27798624)
Novel Interacting Genes		8 novel interacting genes: AGTR1 ATP1B1 CCR4 CLN8 CTDP1 MOB2 RABAC1 TRIM32
Interacting Genes		8 interacting genes: AGTR1 ATP1B1 CCR4 CLN8 CTDP1 MOB2 RABAC1 TRIM32
Entrez ID		57447
HPRD ID		17630
Ensembl ID		ENSG00000165795
Uniprot IDs		Q9UN36
PDB IDs		2XMQ 2XMR 2XMS
Enriched GO Terms of Interacting Partners?		Tat Protein Binding Calcium-mediated Signaling Regulation Of Cell Growth Angiotensin Type I Receptor Activity Bradykinin Receptor Binding Protein Transport Into Plasma Membrane Raft Somatic Motor Neuron Differentiation Glutamate Reuptake Retinal Rod Cell Apoptotic Process Regulation Of Striated Muscle Cell Differentiation TFIIF-class Transcription Factor Complex Binding Protein Localization To Phagocytic Vesicle Positive Regulation Of Interleukin-17-mediated Signaling Pathway Actin Ubiquitination Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cytosolic Calcium Ion Concentration Defense Response Regulation Of Growth Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Regulation Of System Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Import Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Protein Localization To Plasma Membrane Raft Protein Transport Into Membrane Raft Homeostatic Process Regulation Of Muscle Cell Differentiation Actin Modification Striated Muscle Myosin Thick Filament
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