PTGER2

Description		prostaglandin E receptor 2
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Prostaglandin E Receptor Activity
	Biological Process	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Nematode Response To Lipopolysaccharide Response To Progesterone Regulation Of Cell Population Proliferation Cellular Response To Prostaglandin E Stimulus
Pathways		Prostanoid ligand receptors G alpha (s) signalling events
Drugs		Treprostinil Alprostadil Dinoprostone Misoprostol Trichostatin A Gemeprost Limaprost Omidenepag isopropyl Rivenprost
Diseases
GWAS
Novel Interacting Genes		3 novel interacting genes: PTGDS PTGES PTGFR
Interacting Genes		3 interacting genes: PTGDS PTGES PTGFR
Entrez ID		5732
HPRD ID		08905
Ensembl ID		ENSG00000125384
Uniprot IDs		P43116
PDB IDs		7CX2 7CX3 7CX4
Enriched GO Terms of Interacting Partners?		Prostaglandin-D Synthase Activity Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Prostanoid Metabolic Process Prostaglandin Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Icosanoid Biosynthetic Process Unsaturated Fatty Acid Metabolic Process Icosanoid Metabolic Process Fatty Acid Biosynthetic Process Prostaglandin F Receptor Activity Isomerase Activity Negative Regulation Of Male Germ Cell Proliferation Prostaglandin-E Synthase Activity Carboxylic Acid Biosynthetic Process Fatty Acid Metabolic Process Regulation Of Cell Population Proliferation Regulation Of Male Germ Cell Proliferation Regulation Of Germ Cell Proliferation Cellular Response To Prostaglandin D Stimulus Regulation Of Fever Generation Parturition Retinoid Binding Glutathione Binding Small Molecule Biosynthetic Process Nuclear Envelope Lumen Monocarboxylic Acid Metabolic Process Positive Regulation Of Prostaglandin Secretion Lipid Biosynthetic Process Positive Regulation Of Icosanoid Secretion Regulation Of Circadian Sleep/wake Cycle, Sleep Glutathione Peroxidase Activity Positive Regulation Of Fatty Acid Transport Response To Hormone Regulation Of Circadian Sleep/wake Cycle Mast Cell Degranulation Small Molecule Binding Cellular Response To Prostaglandin Stimulus Negative Regulation Of Cell Population Proliferation Fatty Acid Binding Organic Acid Metabolic Process Perinuclear Region Of Cytoplasm Carboxylic Acid Metabolic Process Glutathione Transferase Activity Regulation Of Fatty Acid Transport Rough Endoplasmic Reticulum Response To Lipid Leukocyte Degranulation Sensory Perception Of Pain Regulation Of Acute Inflammatory Response
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