ADCK1

Description		aarF domain containing kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function	Nucleotide Binding Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity
	Biological Process	Mitochondrion Organization Negative Regulation Of Mitochondrial Fusion Lipid Homeostasis Positive Regulation Of Cristae Formation
Pathways
Drugs
Diseases
GWAS		Cerebrospinal T-tau levels ( 28247064) Obsessive-compulsive disorder ( 30456828) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy) ( 24554482) Resting heart rate ( 27798624)
Novel Interacting Genes		2 novel interacting genes: EXOC5 RAB1A
Interacting Genes		2 interacting genes: EXOC5 RAB1A
Entrez ID		57143
HPRD ID		10630
Ensembl ID		ENSG00000063761
Uniprot IDs		Q86TW2
PDB IDs
Enriched GO Terms of Interacting Partners?		Secretion By Cell Organelle Localization Cilium Organization Cell Projection Assembly Cilium Assembly Golgi Vesicle Transport Plasma Membrane Bounded Cell Projection Assembly Growth Hormone Secretion Secretion Virion Assembly Vesicle Tethering Involved In Exocytosis Positive Regulation Of Glycoprotein Metabolic Process Establishment Of Melanosome Localization Establishment Of Endothelial Intestinal Barrier Melanosome Localization Plasma Membrane Bounded Cell Projection Organization COPII-coated Vesicle Cargo Loading Melanosome Transport Pigment Granule Transport Organelle Assembly Exocyst Establishment Of Planar Polarity Pigment Granule Localization Vesicle Cargo Loading Vesicle Tethering Protein Transport Cell Projection Organization Vesicle Transport Along Microtubule Vesicle-mediated Transport Establishment Of Protein Localization Substrate Adhesion-dependent Cell Spreading Endothelial Cell Development Establishment Of Endothelial Barrier Epithelial Cell Apoptotic Process Membrane Fission Vesicle Docking Involved In Exocytosis Transport Vesicle Membrane Non-motile Cilium Assembly Vesicle Cytoskeletal Trafficking Positive Regulation Of Interleukin-8 Production Vesicle Docking Golgi To Plasma Membrane Transport Cellular Localization Mitotic Cytokinesis Peptide Hormone Secretion G Protein Activity Peptide Secretion Organelle Localization By Membrane Tethering Hormone Secretion Regulation Of Interleukin-8 Production
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