CYSLTR2

Description		cysteinyl leukotriene receptor 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Cysteinyl Leukotriene Receptor Activity G Protein-coupled Receptor Activity Galanin Receptor Activity Leukotriene Receptor Activity Protein Binding
	Biological Process	Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Leukotriene Signaling Pathway
Pathways		Leukotriene receptors G alpha (q) signalling events G alpha (s) signalling events LTC4-CYSLTR mediated IL4 production
Drugs		Nedocromil Leukotriene C4 Leukotriene D4
Diseases
GWAS		3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Post bronchodilator FEV1/FVC ratio ( 26634245) Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382) Systemic juvenile idiopathic arthritis ( 27927641)
Interacting Genes		19 interacting genes: ATP5MC2 DBI ENO1 GNAS GRIK1 HSP90B1 KRTAP1-1 LNX1 MTUS2 NCKIPSD PCDH9 PCMT1 RNASEK RNF144A RTN4 SVOP TTC19 YIPF6 YWHAE
Entrez ID		57105
HPRD ID		09293
Ensembl ID		ENSG00000152207
Uniprot IDs		A4ZKH2 Q5KU17 Q9NS75
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway
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