TRIM49

Description		tripartite motif containing 49
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Protein Kinase Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Gene Expression Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Intraocular pressure ( 30591961) Response to taxane treatment (docetaxel) ( 23006423) Serum metabolite levels ( 33031748)
Novel Interacting Genes		4 novel interacting genes: BLM LGALS8 MINDY3 POM121
Interacting Genes		4 interacting genes: BLM LGALS8 MINDY3 POM121
Entrez ID		57093
HPRD ID		05840
Ensembl ID		ENSG00000168930
Uniprot IDs		E9PK69 P0CI25
PDB IDs
Enriched GO Terms of Interacting Partners?		8-hydroxy-2'-deoxyguanosine DNA Binding DNA Geometric Change Forked DNA-dependent Helicase Activity Resolution Of DNA Recombination Intermediates Telomeric G-quadruplex DNA Binding DNA/DNA Annealing Activity RecQ Family Helicase-topoisomerase III Complex Telomeric D-loop Binding Four-way Junction Helicase Activity Telomeric D-loop Disassembly Cellular Response To Camptothecin Bubble DNA Binding Y-form DNA Binding G-quadruplex DNA Binding Telomere Maintenance Via Semi-conservative Replication Lymphatic Endothelial Cell Migration Xenophagy Plasma Cell Differentiation Nuclear Membrane T-circle Formation Cellular Response To Hydroxyurea Response To Hydroxyurea Telomeric Loop Disassembly Hydrolase Activity, Acting On Acid Anhydrides, In Phosphorus-containing Anhydrides 3'-5' DNA Helicase Activity Lateral Element Negative Regulation Of Cell Division Four-way Junction DNA Binding DNA Conformation Change K48-linked Deubiquitinase Activity Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding DNA Double-strand Break Processing
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