RARS2

Description		arginyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Membrane Mitochondrial Membrane
	Molecular Function	Nucleotide Binding RNA Binding Aminoacyl-tRNA Ligase Activity Arginine-tRNA Ligase Activity Protein Binding ATP Binding Ligase Activity
	Biological Process	TRNA Metabolic Process Translation TRNA Aminoacylation For Protein Translation Arginyl-tRNA Aminoacylation Gene Expression Mitochondrial Translation
Pathways		Mitochondrial tRNA aminoacylation
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Household income (MTAG) ( 31844048) Initial alcohol sensitivity ( 30276832) Obesity-related traits ( 23251661)
Novel Interacting Genes		2 novel interacting genes: MMS22L OGT
Interacting Genes		2 interacting genes: MMS22L OGT
Entrez ID		57038
HPRD ID		15209
Ensembl ID		ENSG00000146282
Uniprot IDs		A0A8I5KPZ0 A0A8I5KWC6 H0UI22 Q5T160
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity FACT Complex Regulation Of Transcription By Glucose NSL Complex MCM Complex Protein Localization To Organelle Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Nuclear Replication Fork Chromatin Organization Sin3-type Complex Histone Acetyltransferase Complex Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse Regulation Of Receptor Localization To Synapse Regulation Of Necroptotic Process Regulation Of Rac Protein Signal Transduction Mitophagy Protein Localization To Lysosome Circadian Regulation Of Gene Expression Positive Regulation Of Stem Cell Population Maintenance Cellular Response To Glucose Stimulus Regulation Of Stem Cell Population Maintenance Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Carbohydrate Catabolic Process Regulation Of Gluconeogenesis Regulation Of ATP Metabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Cellular Response To Carbohydrate Stimulus Negative Regulation Of Translational Initiation Negative Regulation Of Proteasomal Protein Catabolic Process Phosphatidylinositol-3,4,5-trisphosphate Binding Pyroptotic Inflammatory Response Cellular Response To Nutrient Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Autophagy Of Mitochondrion Positive Regulation Of Translational Initiation Negative Regulation Of Protein Ubiquitination TORC1 Signaling Regulation Of Insulin Receptor Signaling Pathway Regulation Of Programmed Necrotic Cell Death Replication Fork Processing
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