BDH2

Description		3-hydroxybutyrate dehydrogenase 2
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Cytosol Extracellular Exosome
	Molecular Function	3-hydroxybutyrate Dehydrogenase Activity Protein Binding Oxidoreductase Activity 4-oxoproline Reductase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors, NAD Or NADP As Acceptor NAD Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Beta-oxidation Siderophore Biosynthetic Process Epithelial Cell Differentiation Heme Metabolic Process
Pathways		Synthesis of Ketone Bodies
Drugs
Diseases
GWAS		Pulse pressure ( 30578418) Schizophrenia ( 28991256)
Novel Interacting Genes		3 novel interacting genes: CFTR NFYC SNCA
Interacting Genes		3 interacting genes: CFTR NFYC SNCA
Entrez ID		56898
HPRD ID		07103
Ensembl ID		ENSG00000164039
Uniprot IDs		Q9BUT1
PDB IDs		2AG5
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Exocytosis Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Exocytosis Positive Regulation Of Anion Channel Activity Organic Hydroxy Compound Transport Positive Regulation Of Monoatomic Ion Transport Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Positive Regulation Of Enamel Mineralization Transcription Cis-regulatory Region Binding Negative Regulation Of Dopamine Metabolic Process Regulation Of Serotonin Uptake Regulation Of Monoatomic Ion Transmembrane Transport Transepithelial Water Transport Positive Regulation Of Secretion By Cell CCAAT-binding Factor Complex Negative Regulation Of Thrombin-activated Receptor Signaling Pathway Negative Regulation Of Catecholamine Metabolic Process Positive Regulation Of Secretion Positive Regulation Of Tooth Mineralization Dopamine Uptake Involved In Synaptic Transmission Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Response To Iron(II) Ion Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Regulation Of Chaperone-mediated Autophagy Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Oxidative Phosphorylation Enzyme Binding Amelogenesis Regulation Of Monoatomic Ion Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Mitochondrial ATP Synthesis Coupled Electron Transport Cuprous Ion Binding
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