KCNQ5

Description		potassium voltage-gated channel subfamily Q member 5
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GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Clathrin Coat Monoatomic Ion Channel Complex Presynaptic Membrane Calyx Of Held
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential
Pathways		Voltage gated Potassium channels
Drugs		Enflurane Gabapentin Promethazine Miconazole Ezogabine ICA-105665
Diseases
GWAS		Carotid plaque burden ( 28282560) Cataracts ( 34127677) Frontal pole volume ( 31530798) High myopia ( 31816047) HIV-1 viral setpoint ( 26039976) Lung function (FEV1/FVC) ( 28166213 30804560) Lung function (FVC) ( 30804560) Myopia ( 27182965) Optic disc size ( 31809533) Peak expiratory flow ( 30804560) Periodontitis ( 25672891) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Pulse pressure ( 30224653) Refractive error ( 23396134 32231278) Rosacea symptom severity ( 29771307) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Total body bone mineral density ( 30172743) Upper eyelid sagging severity ( 24869959) Western dietary pattern ( 28644415)
Novel Interacting Genes		8 novel interacting genes: CALM1 CALM2 CALM3 DISC1 KCNQ3 MTDH POU3F2 SRC
Interacting Genes		8 interacting genes: CALM1 CALM2 CALM3 DISC1 KCNQ3 MTDH POU3F2 SRC
Entrez ID		56479
HPRD ID		16241
Ensembl ID		ENSG00000185760
Uniprot IDs		Q9NR82
PDB IDs		6B8Q
Enriched GO Terms of Interacting Partners?		Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Voltage-gated Potassium Channel Complex Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Heart Rate Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Calcium Channel Complex Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcineurin-mediated Signaling Presynaptic Cytosol Transmembrane Transporter Binding Response To Calcium Ion Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Modulation Of Chemical Synaptic Transmission Calcium Channel Regulator Activity Regulation Of Heart Contraction Sperm Midpiece Regulation Of Synaptic Plasticity Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcomere Cell Cycle G2/M Phase Transition Regulation Of Action Potential Neural Nucleus Development Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Detection Of Stimulus Regulation Of Blood Circulation Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Monoatomic Ion Transmembrane Transport Negative Regulation Of Voltage-gated Calcium Channel Activity
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