BAIAP2L1

Description		BAR/IMD domain containing adaptor protein 2 like 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Actin Cytoskeleton Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Proline-rich Region Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Plasma Membrane Organization Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly Actin Crosslink Formation Cell-cell Adhesion
Pathways		RAC1 GTPase cycle RAC2 GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) LDL cholesterol levels ( 32203549) Liver enzyme levels (alkaline phosphatase) ( 33972514) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Pursuit maintenance gain ( 29064472) Sex hormone-binding globulin levels ( 22829776) White blood cell count ( 32888494)
Novel Interacting Genes		10 novel interacting genes: BAG3 CYSRT1 FASLG KHDRBS1 LANCL1 MDM2 NEDD4 TP53 WAS YWHAG
Interacting Genes		10 interacting genes: BAG3 CYSRT1 FASLG KHDRBS1 LANCL1 MDM2 NEDD4 TP53 WAS YWHAG
Entrez ID		55971
HPRD ID		11270
Ensembl ID		ENSG00000006453
Uniprot IDs		Q9UHR4
PDB IDs		2KXC 2LNH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Protein Stability Regulation Of Nucleocytoplasmic Transport Cellular Response To Actinomycin D Response To Actinomycin D Cellular Response To UV-C Protein Domain Specific Binding Regulation Of Biological Quality Regulation Of Intracellular Transport Cellular Response To Antibiotic Cellular Response To UV Signal Transduction Necroptotic Process Cellular Response To Light Stimulus Response To UV-C Striated Muscle Cell Apoptotic Process SH3 Domain Binding Positive Regulation Of Transport Muscle Cell Apoptotic Process Positive Regulation Of Protein Export From Nucleus Programmed Necrotic Cell Death Response To UV Disordered Domain Specific Binding Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Gamma Radiation Cellular Response To Radiation T Cell Apoptotic Process Regulation Of Cellular Localization Regulation Of Macroautophagy Identical Protein Binding Lymphocyte Apoptotic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of Protein Export From Nucleus Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Stabilization Leukocyte Apoptotic Process Protein Localization To Organelle DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Translational Initiation Cellular Response To Nutrient Levels Cell Activation Cellular Response To Glucose Starvation Establishment Of Protein Localization Response To Gamma Radiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination
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