CENPN

Description		centromere protein N
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Protein Binding
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444 31624269) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: ALKBH7 DNAAF19 OSGIN1 TSSK3
Entrez ID		55839
HPRD ID		12528
Ensembl ID		ENSG00000166451
Uniprot IDs		Q96H22
PDB IDs		6BUZ 6C0W 6EQT 6MUO 6MUP 7PKN 7QOO 7R5S 7R5V 7U46 7U47 7U4D 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?
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