PRKCH

Description		protein kinase C eta
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GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Extracellular Exosome
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Protein Kinase Inhibitor Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Enzyme Binding Protein Serine/threonine Kinase Inhibitor Activity Small GTPase Binding Translation Regulator Activity Metal Ion Binding Protein Serine Kinase Activity Protein Serine/threonine Kinase Binding
	Biological Process	Regulation Of Translation Protein Phosphorylation Signal Transduction Positive Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Translation Cell Differentiation Positive Regulation Of Translation In Response To Stress Cellular Response To Amino Acid Starvation Negative Regulation Of Glial Cell Apoptotic Process Intracellular Signal Transduction Positive Regulation Of Keratinocyte Differentiation Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Glial Cell Proliferation Phospholipase C/protein Kinase C Signal Transduction Positive Regulation Of Protein Localization To Plasma Membrane Regulation Of Bicellular Tight Junction Assembly
Pathways		Effects of PIP2 hydrolysis G alpha (z) signalling events
Drugs
Diseases
GWAS		Asthma ( 32296059) Height ( 28552196) Obesity (early onset extreme) ( 23563609) Reading and spelling ( 23738518) Rheumatoid arthritis ( 22446963 24390342 30423114) Word reading ( 23738518) Yeast infection ( 28928442)
Novel Interacting Genes		17 novel interacting genes: BANP BMP4 C14orf39 CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SIX6 SRC ZBTB8OS ZFP36L1 ZFYVE1
Interacting Genes		17 interacting genes: BANP BMP4 C14orf39 CDK2 FYN GSK3A ITGB2 NUMB PARD6A PPP1R14A PRKD1 PTPN11 SIX6 SRC ZBTB8OS ZFP36L1 ZFYVE1
Entrez ID		5583
HPRD ID		05669
Ensembl ID		ENSG00000027075
Uniprot IDs		P24723
PDB IDs		2FK9 3TXO 8FP1 8FP3
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Localization Regulation Of Protein Localization Cellular Response To Growth Factor Stimulus Regulation Of Establishment Of Protein Localization Response To Growth Factor Forebrain Development Cellular Response To Peptide Hormone Stimulus Positive Regulation Of Protein Localization To Nucleus Integrin-mediated Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Transport Positive Regulation Of Multicellular Organismal Process Response To Peptide Hormone Positive Regulation Of Establishment Of Protein Localization T Cell Costimulation Regulation Of Protein Localization To Nucleus Cellular Response To Hormone Stimulus Ephrin Receptor Signaling Pathway Negative Regulation Of Neutrophil Activation Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Multicellular Organismal Development Regulation Of Leukocyte Cell-cell Adhesion Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Phospholipase Activator Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Peptide Hormone Receptor Binding Regulation Of Neutrophil Activation Positive Regulation Of Protein Localization BMP Receptor Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Neutrophil Activation Involved In Immune Response Cellular Response To Steroid Hormone Stimulus Regulation Of Cell Adhesion Regulation Of Striated Muscle Cell Differentiation Protein Kinase Activity Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Intracellular Transport Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Cellular Response To Chemical Stress Negative Regulation Of Cell Cycle Process Cellular Response To Oxygen-containing Compound Positive Regulation Of Leukocyte Cell-cell Adhesion Cell Differentiation Regulation Of Developmental Process Leukocyte Activation Tau-protein Kinase Activity Stimulatory C-type Lectin Receptor Signaling Pathway
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