TRERF1

Description		transcriptional regulating factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytosol
	Molecular Function	Transcription Coactivator Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Nuclear Progesterone Receptor Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Progesterone Receptor Signaling Pathway Cellular Response To Progesterone Stimulus
Pathways
Drugs
Diseases
GWAS		Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Falling risk ( 32999390) HDL cholesterol levels in HIV infection ( 33109212) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of granulocytes ( 27863252) Serum total protein levels ( 29403010) Sum eosinophil basophil counts ( 27863252)
Novel Interacting Genes		8 novel interacting genes: CREBBP EP300 ESRRG ITCH KEAP1 NEDD4 NR5A1 YAP1
Interacting Genes		8 interacting genes: CREBBP EP300 ESRRG ITCH KEAP1 NEDD4 NR5A1 YAP1
Entrez ID		55809
HPRD ID		11647
Ensembl ID		ENSG00000124496
Uniprot IDs		A0A8Q3SI57 Q05GC8 Q96PN7
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Cellular Response To Radiation Histone H3K27 Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Intracellular Signal Transduction Positive Regulation Of Macromolecule Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Cellular Response To UV Nucleoplasm Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Localization To Nucleus N-terminal Protein Amino Acid Acetylation Cellular Response To Light Stimulus Peptidyl-lysine Acetylation Regulation Of Cellular Response To Heat Transcription Coregulator Activity Acetyltransferase Activity Chromatin Binding Regulation Of Macromolecule Biosynthetic Process Response To UV Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway Response To Radiation Regulation Of Gene Expression Regulation Of Protein Localization To Nucleus Hormone-mediated Signaling Pathway Proline-rich Region Binding Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Regulation Of RNA Biosynthetic Process Chromatin Histone Acetyltransferase Complex Protein-lysine-acetyltransferase Activity Innate Immune Response-activating Signaling Pathway DNA-binding Transcription Factor Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of RNA Metabolic Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Histone Acetyltransferase Activity Activation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Protein Catabolic Process Protein Acetylation Regulation Of Macromolecule Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process
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