AGK

Description		acylglycerol kinase
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Mitochondrial Membrane TIM22 Mitochondrial Import Inner Membrane Insertion Complex
	Molecular Function	Nucleotide Binding Lipid Kinase Activity Ceramide Kinase Activity ATP-dependent Diacylglycerol Kinase Activity Protein Binding ATP Binding Sphingosine Kinase Activity Kinase Activity Transferase Activity Acylglycerol Kinase Activity
	Biological Process	Lipid Metabolic Process Protein Insertion Into Mitochondrial Inner Membrane Glycerolipid Metabolic Process Sphingosine Biosynthetic Process Ceramide Biosynthetic Process Lipid Phosphorylation
Pathways		Glycerophospholipid biosynthesis Signaling by BRAF and RAF1 fusions
Drugs
Diseases
GWAS		Mood disorder and prion disease ( 25897833) Psoriasis ( 31376382)
Novel Interacting Genes		3 novel interacting genes: HCK PDLIM1 SNX4
Interacting Genes		3 interacting genes: HCK PDLIM1 SNX4
Entrez ID		55750
HPRD ID		08554
Ensembl ID		ENSG00000006530
Uniprot IDs		A0A3B3ISZ0 A4D1U5 Q53H12
PDB IDs		7CGP
Enriched GO Terms of Interacting Partners?		Respiratory Burst After Phagocytosis Leukocyte Migration Involved In Immune Response Regulation Of Organelle Assembly Leptin Receptor Binding Positive Regulation Of Histamine Secretion By Mast Cell Establishment Or Maintenance Of Actin Cytoskeleton Polarity Type II Interferon-mediated Signaling Pathway Regulation Of Podosome Assembly Positive Regulation Of Cellular Component Biogenesis Lipid Binding Respiratory Burst Involved In Defense Response Focal Adhesion Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Respiratory Burst Regulation Of Inflammatory Response Positive Regulation Of Organelle Organization Positive Regulation Of Defense Response Regulation Of Vesicle-mediated Transport Cytoplasmic Dynein Complex Regulation Of Histamine Secretion By Mast Cell Positive Regulation Of Autophagosome Assembly Transferrin Receptor Binding Insulin Receptor Binding Positive Regulation Of Mast Cell Degranulation Presynaptic Endosome Muscle Alpha-actinin Binding Maintenance Of Cell Polarity Cadherin Binding Involved In Cell-cell Adhesion Contractile Actin Filament Bundle Assembly Stress Fiber Assembly Fibroblast Migration Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Vacuole Organization Filamentous Actin Regulation Of Mast Cell Degranulation Negative Regulation Of Inflammatory Response To Antigenic Stimulus Fc-gamma Receptor Signaling Pathway Epidermal Growth Factor Receptor Binding Phosphotyrosine Residue Binding Regulation Of Defense Response Cell Adhesion Cell Migration Leukocyte Degranulation Positive Regulation Of Actin Filament Polymerization Non-membrane Spanning Protein Tyrosine Kinase Activity Lipopolysaccharide-mediated Signaling Pathway SNARE Complex Positive Regulation Of Regulated Secretory Pathway Regulation Of Autophagosome Assembly Phosphatidylinositol-3-phosphate Binding
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