TENM3

Description		teneurin transmembrane protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Axon Cell Projection Neuron Projection
	Molecular Function	Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Positive Regulation Of Neuron Projection Development Cell Differentiation Camera-type Eye Morphogenesis Neuron Development Regulation Of Homophilic Cell Adhesion
Pathways
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Bortezomib-induced peripheral neuropathy in multiple myeloma ( 28317148) Chronic kidney disease x type 2 diabetes interaction ( 32541925) Colorectal cancer (calcium intake interaction) ( 25192705) Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189) Ferritin levels ( 33491795) General factor of neuroticism ( 30867560) General risk tolerance (MTAG) ( 30643258) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) Hand grip strength ( 29691431) JT interval (sulfonylurea treatment interaction) ( 27958378) Oropharynx cancer ( 27749845) Plasma renin activity levels ( 25477429) Refractive error ( 32231278) Schizophrenia ( 33169155) Smoking initiation ( 24665060)
Novel Interacting Genes		1 novel interacting genes: SMAD4
Interacting Genes		1 interacting genes: SMAD4
Entrez ID		55714
HPRD ID		14874
Ensembl ID		ENSG00000218336
Uniprot IDs		A0A140VJW8 Q9P273
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Activin Responsive Factor Complex Left Ventricular Cardiac Muscle Tissue Morphogenesis Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis Metanephric Mesenchyme Morphogenesis SMAD Protein Complex Positive Regulation Of Luteinizing Hormone Secretion Regulation Of Follicle-stimulating Hormone Secretion Positive Regulation Of Follicle-stimulating Hormone Secretion Atrioventricular Valve Formation Sebaceous Gland Development Heteromeric SMAD Protein Complex Formation Of Anatomical Boundary Brainstem Development Mesendoderm Development Sulfate Binding Positive Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Transforming Growth Factor Beta2 Production Endocardial Cell Differentiation Atrioventricular Canal Development Somite Rostral/caudal Axis Specification Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Cardiac Muscle Cell Differentiation Endothelial Cell Activation Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Negative Regulation Of Cardiocyte Differentiation Secondary Palate Development Filamin Binding Neural Crest Cell Differentiation Heart Valve Formation Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Cardiac Muscle Cell Apoptotic Process I-SMAD Binding Cardiac Conduction System Development Interleukin-6-mediated Signaling Pathway Gastrulation With Mouth Forming Second Regulation Of Cell Proliferation Involved In Heart Morphogenesis Regulation Of Cardiac Muscle Cell Differentiation Seminiferous Tubule Development Regulation Of Hair Follicle Development Regulation Of Extracellular Matrix Assembly Uterus Development Female Gonad Development Positive Regulation Of Extracellular Matrix Organization Outflow Tract Septum Morphogenesis SMAD Protein Signal Transduction Regulation Of Hair Cycle
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