NECAP2

Description		NECAP endocytosis associated 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Clathrin-coated Pit Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding
	Biological Process	Endocytosis Protein Transport Vesicle-mediated Transport
Pathways		Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS
Novel Interacting Genes		6 novel interacting genes: AP2B1 APP NMI PLSCR1 SNCA TRAF2
Interacting Genes		6 interacting genes: AP2B1 APP NMI PLSCR1 SNCA TRAF2
Entrez ID		55707
HPRD ID		07674
Ensembl ID		ENSG00000157191
Uniprot IDs		F6SKB8 Q9NVZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Activation Macrophage Activation Regulation Of Endocytosis Enzyme Binding Positive Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Response To Lead Ion Positive Regulation Of Inflammatory Response Response To External Biotic Stimulus Positive Regulation Of Defense Response Myeloid Leukocyte Activation Regulation Of Neurotransmitter Uptake Leukocyte Activation Cellular Response To Copper Ion Membrane Raft Regulation Of Presynapse Organization Regulation Of Immune System Process Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Amyloid Fibril Formation Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Synaptic Vesicle Endocytosis Regulation Of Defense Response Neurotransmitter Secretion Presynaptic Endocytosis Apoptotic Process Chemical Synaptic Transmission Positive Regulation Of Phosphate Metabolic Process Programmed Cell Death Cell Death Regulation Of Immune Response Response To Metal Ion Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Immune System Process Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Other Organism Regulation Of Cellular Component Organization Receptor Internalization Endocytosis Clathrin-coated Pit Positive Regulation Of Protein Localization Amyloid-beta Complex Response To Interleukin-1 Growth Cone Lamellipodium
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