NDC1

Description		NDC1 transmembrane nucleoporin
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Cytoplasm Plasma Membrane Actin Cytoskeleton Membrane Nuclear Membrane Nuclear Pore Transmembrane Ring
	Molecular Function	Structural Constituent Of Nuclear Pore Protein-macromolecule Adaptor Activity
	Biological Process	Nucleocytoplasmic Transport Nuclear Pore Organization Homologous Chromosome Pairing At Meiosis Spermatogenesis Protein Transport MRNA Transport Nuclear Pore Complex Assembly Nuclear Pore Localization
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Response to antidepressants and depression ( 27622933)
Novel Interacting Genes		4 novel interacting genes: DNM2 NUP93 UBC ZYG11B
Interacting Genes		4 interacting genes: DNM2 NUP93 UBC ZYG11B
Entrez ID		55706
HPRD ID		08547
Ensembl ID		ENSG00000058804
Uniprot IDs		Q9BTX1
PDB IDs		7R5J 7R5K
Enriched GO Terms of Interacting Partners?		Endocytic Vesicle Membrane Negative Regulation Of Membrane Tubulation Vesicle Scission
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