NSUN5

Description		NOP2/Sun RNA methyltransferase 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus
	Molecular Function	RNA Binding Methyltransferase Activity RNA Methyltransferase Activity RRNA (cytosine-C5-)-methyltransferase Activity Transferase Activity
	Biological Process	RNA Methylation RRNA Processing Oligodendrocyte Development Cerebral Cortex Development Corpus Callosum Development Regulation Of Myelination Methylation Positive Regulation Of Translation Cognition RRNA Base Methylation
Pathways
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)
Novel Interacting Genes		4 novel interacting genes: CEBPA OGT PTPN11 VHL
Interacting Genes		4 interacting genes: CEBPA OGT PTPN11 VHL
Entrez ID		55695
HPRD ID		11678
Ensembl ID		ENSG00000130305
Uniprot IDs		Q96P11
PDB IDs		2B9E
Enriched GO Terms of Interacting Partners?		Carbohydrate Homeostasis Glucose Homeostasis Positive Regulation Of Biosynthetic Process Negative Regulation Of Developmental Process Negative Regulation Of Cell Population Proliferation Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Chromatin DNA Binding CHOP-C/EBP Complex Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Metabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Cell Development Protein-containing Complex Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Binding RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Nutrient Chemical Homeostasis Response To Vitamin B2 Positive Regulation Of Macromolecule Biosynthetic Process C/EBP Complex Inner Ear Development Regulation Of Developmental Process Negative Regulation Of Cortisol Secretion Molecular Adaptor Activity Negative Regulation Of Growth Hormone Secretion Hemopoiesis Intestinal Epithelial Cell Migration Regulation Of Insulin Receptor Signaling Pathway Cerebellar Cortex Formation Regulation Of TOR Signaling Regulation Of TORC1 Signaling Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Stress White Fat Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Negative Regulation Of Gene Expression Negative Regulation Of Glucocorticoid Secretion Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Negative Regulation Of Multicellular Organismal Process Myeloid Cell Differentiation
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