LIMS2

Description		LIM zinc finger domain containing 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Focal Adhesion Membrane Anchoring Junction
	Molecular Function	Protein Binding Metal Ion Binding
	Biological Process	Integrin-mediated Signaling Pathway Negative Regulation Of Apoptotic Process Cell-cell Junction Organization Neural Precursor Cell Proliferation Cell-cell Adhesion Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cholangiocyte Proliferation Cholangiocyte Proliferation Negative Regulation Of Neural Precursor Cell Proliferation Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways		Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Alzheimer's disease (cognitive decline) ( 23535033) Type 2 diabetes ( 25483131)
Novel Interacting Genes		18 novel interacting genes: APP CALCOCO2 GOLGA2 HIPK3 HOXA1 HRH1 ILK KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 LMNA MDFI MTUS2 NOTCH2NLA RCHY1 TRIM55 TRIM63
Interacting Genes		18 interacting genes: APP CALCOCO2 GOLGA2 HIPK3 HOXA1 HRH1 ILK KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 LMNA MDFI MTUS2 NOTCH2NLA RCHY1 TRIM55 TRIM63
Entrez ID		55679
HPRD ID		06389
Ensembl ID		ENSG00000072163
Uniprot IDs		B3KNZ3 Q7Z4I7
PDB IDs		3IXE
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Visual Behavior
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