TTC27

Description		tetratricopeptide repeat domain 27
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Haemorrhoidal disease ( 33888516) Hippocampal atrophy ( 22745009) Intelligence (MTAG) ( 29326435) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Number of sexual partners ( 30643258) Rosacea symptom severity ( 29771307) Upper eyelid sagging severity ( 24869959)
Novel Interacting Genes		9 novel interacting genes: ACVR1 BMPR1B CRYAA DAPK1 EMC1 ITSN1 LRRK2 MFHAS1 TGFBR1
Interacting Genes		9 interacting genes: ACVR1 BMPR1B CRYAA DAPK1 EMC1 ITSN1 LRRK2 MFHAS1 TGFBR1
Entrez ID		55622
HPRD ID		08618
Ensembl ID		ENSG00000018699
Uniprot IDs		B4DRC7 Q6P3X3
PDB IDs
Enriched GO Terms of Interacting Partners?		Transforming Growth Factor Beta Receptor Activity, Type I Transmembrane Receptor Protein Serine/threonine Kinase Activity Protein Serine/threonine Kinase Activity SMAD Binding Protein Kinase Activity Activin Receptor Complex Activin Receptor Activity, Type I Kinase Activity BMP Receptor Activity Positive Regulation Of Cardiac Epithelial To Mesenchymal Transition Activin Binding Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Process Pharyngeal System Development Negative Regulation Of Programmed Cell Death Syntaxin-1 Binding Transforming Growth Factor Beta Binding Nucleotide Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Activin Receptor Signaling Pathway Cellular Response To BMP Stimulus Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Programmed Cell Death Regulation Of Signal Transduction Response To Stress Ventricular Septum Morphogenesis Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Bone Mineralization Lens Development In Camera-type Eye Growth Factor Binding Cellular Response To Growth Factor Stimulus ATP Binding Regulation Of Cell Communication Positive Regulation Of Biomineral Tissue Development Regulation Of Signaling Regionalization Regulation Of Chondrocyte Differentiation Positive Regulation Of Ossification Animal Organ Development Regulation Of Macrophage Activation Negative Regulation Of Intracellular Transport Anatomical Structure Morphogenesis Endocardial Cushion Cell Fate Commitment Dorsal/ventral Pattern Formation
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