KIF16B

Description		kinesin family member 16B
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GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Spindle Cytosol Cytoskeleton Kinesin Complex Microtubule Membrane Cytoplasmic Vesicle Early Endosome Membrane
	Molecular Function	Nucleotide Binding Microtubule Motor Activity Protein Binding ATP Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Microtubule Binding Lipid Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity Phosphatidylinositol-3-phosphate Binding Phosphatidylinositol Binding Phosphatidylinositol-3,4-bisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Formation Of Primary Germ Layer Regulation Of Receptor Recycling Golgi To Endosome Transport Microtubule-based Movement Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Endoderm Development Fibroblast Growth Factor Receptor Signaling Pathway Vesicle-mediated Transport Receptor Catabolic Process Early Endosome To Late Endosome Transport Vesicle Transport Along Microtubule
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Alanine aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Asthma ( 27611488) Body mass index ( 26426971) Chronotype ( 30696823) Dimensional psychopathology (Positive) ( 29496196) Emphysema imaging phenotypes ( 26030696) Gut microbiota alpha diversity (Chao1 index) ( 33208821) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Gut microbiota alpha diversity (Shannon index) ( 33208821) Gut microbiota relative abundance (unclassified genus belonging to family Ruminococcaceae) ( 33208821) HDL cholesterol levels in HIV infection ( 33109212) Hodgkin's lymphoma ( 34216518) Ileal carcinoids ( 21139019) Intelligence ( 22449649) LDL cholesterol levels in HIV infection ( 33109212) Lipid traits ( 30576415) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Post bronchodilator FEV1/FVC ratio ( 26634245) Sweet taste preference ( 32572145)
Novel Interacting Genes		10 novel interacting genes: GABARAPL2 GINS4 IL16 ITSN1 LGALS3 PRKAA1 PRKAA2 SMYD1 TCEANC TSR2
Interacting Genes		10 interacting genes: GABARAPL2 GINS4 IL16 ITSN1 LGALS3 PRKAA1 PRKAA2 SMYD1 TCEANC TSR2
Entrez ID		55614
HPRD ID		10731
Ensembl ID		ENSG00000089177
Uniprot IDs		A0A140VK74 A0A1B0GTU3 A0A1B0GVS8 Q96L93
PDB IDs		2V14 6EE0
Enriched GO Terms of Interacting Partners?		Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Protein Localization To Lipid Droplet Negative Regulation Of Tubulin Deacetylation Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Lipid Droplet Disassembly Phosphatidylethanolamine Biosynthetic Process Regulation Of Protein Deacetylation Regulation Of Stress Granule Assembly Nucleotide-activated Protein Kinase Complex Fatty Acid Homeostasis Hepatocyte Apoptotic Process Cellular Response To Prostaglandin E Stimulus Phosphatidylcholine Biosynthetic Process Positive Regulation Of Glycolytic Process Protein K6-linked Ubiquitination Response To Prostaglandin E Positive Regulation Of Release Of Cytochrome C From Mitochondria Cellular Response To Prostaglandin Stimulus Negative Regulation Of Epithelial Cell Apoptotic Process Phosphatidylethanolamine Metabolic Process Cellular Response To Starvation Cholesterol Biosynthetic Process Positive Regulation Of ATP Metabolic Process Lipid Droplet Organization Response To Starvation Sterol Biosynthetic Process Regulation Of Release Of Cytochrome C From Mitochondria Epithelial Cell Apoptotic Process Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation Cellular Response To Glucose Starvation Cellular Response To Nutrient Levels Regulation Of Glycolytic Process Regulation Of Epithelial Cell Apoptotic Process Protein Localization To Lysosome Cellular Response To Amino Acid Starvation Negative Regulation Of TORC1 Signaling Regulation Of Carbohydrate Catabolic Process Cellular Response To Xenobiotic Stimulus Autophagy Negative Regulation Of Glucosylceramide Biosynthetic Process Cellular Response To Glucose Stimulus Response To Amino Acid Starvation Positive Regulation Of TORC1 Signaling Phosphatidylcholine Metabolic Process TORC1 Signaling Energy Homeostasis
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