TRIM36

Description		tripartite motif containing 36
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GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Vesicle
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Alpha-tubulin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Mitotic Cytokinesis Spindle Organization Acrosome Reaction Regulation Of Cell Cycle Regulation Of Microtubule Cytoskeleton Organization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27618452 27841878 28739976 30487518) Diastolic blood pressure (cigarette smoking interaction) ( 29455858) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Left-handedness ( 32989287) Malaria ( 31844061) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure ( 27618452 27841878 28739976) Systolic blood pressure (cigarette smoking interaction) ( 29455858)
Novel Interacting Genes		11 novel interacting genes: BTRC EIF4A2 GLRX3 GRB7 TRAF3IP3 UBC UBE2D2 UBE2H ZMAT2 ZNF417 ZNF587
Interacting Genes		11 interacting genes: BTRC EIF4A2 GLRX3 GRB7 TRAF3IP3 UBC UBE2D2 UBE2H ZMAT2 ZNF417 ZNF587
Entrez ID		55521
HPRD ID		15554
Ensembl ID		ENSG00000152503
Uniprot IDs		E9PBG3 Q4R1Q4 Q9NQ86
PDB IDs		7QS4
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Negative Regulation Of RNA-dependent RNA Polymerase Activity Proteolysis Involved In Protein Catabolic Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Polyubiquitination Ubiquitin Conjugating Enzyme Activity Protein Phosphorylated Amino Acid Binding Post-translational Protein Modification
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