BATF3

Description		basic leucine zipper ATF-like transcription factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol RNA Polymerase II Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Response To Virus Myeloid Dendritic Cell Differentiation Dendritic Cell Differentiation Integrated Stress Response Signaling
Pathways
Drugs
Diseases
GWAS		Asthma ( 32296059) Leprosy ( 25642632) Multiple sclerosis ( 31604244) Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) ( 29923122) Type 1 diabetes ( 34012112)
Novel Interacting Genes		21 novel interacting genes: AGXT APPL1 ATF3 ATF4 BACH2 BATF CEBPA CEBPE CEBPG CRK DBP DDIT3 EPAS1 FOSL1 GPATCH2L MAFF MAFG NFATC2IP PGR RHOXF2 STAT3
Interacting Genes		21 interacting genes: AGXT APPL1 ATF3 ATF4 BACH2 BATF CEBPA CEBPE CEBPG CRK DBP DDIT3 EPAS1 FOSL1 GPATCH2L MAFF MAFG NFATC2IP PGR RHOXF2 STAT3
Entrez ID		55509
HPRD ID		18081
Ensembl ID		ENSG00000123685
Uniprot IDs		Q9NR55
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Transcription Regulator Complex DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Integrated Stress Response Signaling Chromatin Sequence-specific Double-stranded DNA Binding Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA Binding Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Regulation Of Primary Metabolic Process Identical Protein Binding Regulation Of Metabolic Process CHOP-ATF3 Complex CHOP-ATF4 Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Epithelial Cell Maturation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Intracellular Signaling Cassette CHOP-C/EBP Complex Transcription Regulator Complex DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Myeloid Cell Differentiation Transcription Cis-regulatory Region Binding Developmental Process GDF15-GFRAL Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Cytokine Production MRNA Transcription By RNA Polymerase II Cellular Developmental Process
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