CHST12

Description		carbohydrate sulfotransferase 12
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Sulfotransferase Activity Transferase Activity Chondroitin 4-sulfotransferase Activity 3'-phosphoadenosine 5'-phosphosulfate Binding
	Biological Process	Carbohydrate Biosynthetic Process Proteoglycan Biosynthetic Process Chondroitin Sulfate Proteoglycan Biosynthetic Process Dermatan Sulfate Proteoglycan Biosynthetic Process
Pathways		CS-GAG biosynthesis
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Diastolic blood pressure ( 27618452 27841878 28739976) Dimensional psychopathology (Social) ( 29496196) Multiple sclerosis ( 21833088 31604244) Neutrophil count ( 32888494) Systolic blood pressure ( 27618452 27841878)
Novel Interacting Genes		2 novel interacting genes: MAD1L1 SLC22A1
Interacting Genes		2 interacting genes: MAD1L1 SLC22A1
Entrez ID		55501
HPRD ID		13056
Ensembl ID		ENSG00000136213
Uniprot IDs		Q9NRB3
PDB IDs
Enriched GO Terms of Interacting Partners?		(R)-carnitine Transmembrane Transport Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity Spermidine Transport Metanephric Proximal Tubule Development Epinephrine Transport Norepinephrine:sodium Symporter Activity (R)-carnitine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity O-acyl-L-carnitine Transmembrane Transport Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Deactivation Of Mitotic Spindle Assembly Checkpoint Mitotic Spindle Assembly Checkpoint MAD1-MAD2 Complex MAD1 Complex Negative Regulation Of Mitotic Spindle Assembly Checkpoint Signaling Carnitine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Proximal Tubule Development Carnitine Transmembrane Transport Polyamine Transmembrane Transport Kinetochore Binding Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Positive Regulation Of Mitotic Sister Chromatid Segregation Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Amino-acid Betaine Transport Quaternary Ammonium Group Transport Catecholamine Uptake Dopamine Uptake Prostaglandin Transport Serotonin Transport Metanephric Nephron Tubule Development Pyrimidine-containing Compound Transmembrane Transport Nuclear Pore Nuclear Basket Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
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