PRELP

Description		proline and arginine rich end leucine rich repeat protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Lumen Extracellular Matrix Lysosomal Lumen Extracellular Exosome Extracellular Vesicle
	Molecular Function	Extracellular Matrix Structural Constituent Heparin Binding Extracellular Matrix Structural Constituent Conferring Compression Resistance
	Biological Process	Skeletal System Development Cellular Senescence
Pathways		Keratan sulfate biosynthesis Keratan sulfate degradation Defective CHST6 causes MCDC1 Defective ST3GAL3 causes MCT12 and EIEE15 Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297)
Novel Interacting Genes		7 novel interacting genes: CHAF1B COL1A1 COL2A1 FBLN2 FN1 HSPG2 NID1
Interacting Genes		7 interacting genes: CHAF1B COL1A1 COL2A1 FBLN2 FN1 HSPG2 NID1
Entrez ID		5549
HPRD ID		03556
Ensembl ID		ENSG00000188783
Uniprot IDs		P51888
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Structural Constituent Extracellular Matrix Proteoglycan Binding Basement Membrane Regulation Of Cell-substrate Adhesion Regulation Of Cell Adhesion Fibrillar Collagen Trimer Platelet-derived Growth Factor Binding Positive Regulation Of Cell-substrate Adhesion Extracellular Region Cartilage Development Involved In Endochondral Bone Morphogenesis Endochondral Ossification Extracellular Matrix Binding Extracellular Matrix Organization Extracellular Matrix Structural Constituent Conferring Tensile Strength Extracellular Structure Organization Anatomical Structure Formation Involved In Morphogenesis Endoplasmic Reticulum Lumen Collagen Fibril Organization Collagen Binding Cellular Response To Vitamin E Collagen Trimer System Development Cartilage Development Collagen Type I Trimer Protease Binding Cellular Response To Fluoride Positive Regulation Of Cell Adhesion Cell-matrix Adhesion Collagen V Binding Skeletal System Morphogenesis Ossification Collagen Type II Trimer Negative Regulation Of Monocyte Activation Positive Regulation Of Substrate-dependent Cell Migration, Cell Attachment To Substrate CAF-1 Complex Animal Organ Development Calcium Ion Binding Response To Fluoride Sensory Perception Of Mechanical Stimulus Sensory Perception Of Sound Extracellular Space Calcium-independent Cell-matrix Adhesion Integrin Binding Cell-substrate Adhesion Collagen Type XI Trimer Anterior Head Development Intramembranous Ossification Visual Perception Skeletal System Development
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