STK32B

Description		serine/threonine kinase 32B
Image		No pdb structure
GO Annotations	Cellular Component
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Age at suicide ( 31476763) Alzheimer's disease ( 30636644) Alzheimer's disease (cognitive decline) ( 23535033) Alzheimer's disease progression score ( 29860282) Celiac disease ( 23936387) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) Essential tremor ( 27797806) Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio) ( 33987465) Sensory disturbances after bilateral sagittal split ramus osteotomy ( 23834954) Vascular endothelial growth factor levels ( 31217265)
Novel Interacting Genes		1 novel interacting genes: FGFR3
Interacting Genes		1 interacting genes: FGFR3
Entrez ID		55351
HPRD ID		15446
Ensembl ID		ENSG00000152953
Uniprot IDs		B2R9M8 Q9NY57
PDB IDs
Enriched GO Terms of Interacting Partners?		Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Positive Regulation Of Phospholipase Activity Bone Maturation Fibroblast Growth Factor Receptor Activity Endochondral Bone Growth Positive Regulation Of Lipase Activity Chondrocyte Proliferation Bone Growth Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Fibroblast Growth Factor Binding Regulation Of Tyrosine Phosphorylation Of STAT Protein Endochondral Ossification Bone Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Chondrocyte Differentiation Transmembrane Receptor Protein Tyrosine Kinase Activity Organ Growth Bone Mineralization Fibroblast Growth Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Via JAK-STAT Regulation Of Peptidyl-tyrosine Phosphorylation Cell Surface Receptor Signaling Pathway Via STAT Biomineral Tissue Development Negative Regulation Of Developmental Growth Cartilage Development Transport Vesicle Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Hydrolase Activity Ossification Protein Tyrosine Kinase Activity Skeletal System Development Positive Regulation Of ERK1 And ERK2 Cascade Receptor Complex Developmental Maturation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Growth Positive Regulation Of Protein Phosphorylation MAPK Cascade Positive Regulation Of Phosphorylation Regulation Of ERK1 And ERK2 Cascade Regulation Of Developmental Growth Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphate Metabolic Process Positive Regulation Of Catalytic Activity Apoptotic Signaling Pathway
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