TRIM62

Description		tripartite motif containing 62
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Immune System Process Negative Regulation Of Epithelial To Mesenchymal Transition Protein Ubiquitination Viral Release From Host Cell Negative Regulation Of Viral Transcription Positive Regulation Of Canonical NF-kappaB Signal Transduction Protein K27-linked Ubiquitination Innate Immune Response Positive Regulation Of DNA-templated Transcription Regulation Of Viral Entry Into Host Cell Positive Regulation Of Antifungal Innate Immune Response
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)
Novel Interacting Genes		19 novel interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Interacting Genes		19 interacting genes: CARD9 EAF1 EPN2 EXOSC5 FAIM GLRX PPP1R18 SKIL SMAD2 SP7 TBC1D7 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E3 UBE2L6 UBXN7 UTP25
Entrez ID		55223
HPRD ID		07697
Ensembl ID		ENSG00000116525
Uniprot IDs		Q9BVG3
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Protein Polyubiquitination Regulation Of BMP Signaling Pathway Macromolecule Catabolic Process Negative Regulation Of Cellular Response To Growth Factor Stimulus Protein K11-linked Ubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of BMP Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Post-translational Protein Modification Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein K6-linked Ubiquitination Catabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Nucleoplasm Nucleus Protein-containing Complex SMAD Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Proteolysis Phosphatase Binding Macromolecule Metabolic Process Protein Monoubiquitination Glutathione Disulfide Oxidoreductase Activity Homomeric SMAD Protein Complex TSC1-TSC2 Complex Binding Negative Regulation Of TORC1 Signaling Cellular Response To Nutrient Levels Protein Autoubiquitination Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Negative Regulation Of Signal Transduction Protein K63-linked Ubiquitination TSC1-TSC2 Complex
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