MRM3

Description		mitochondrial rRNA methyltransferase 3
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GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function	RNA Binding Protein Binding Methyltransferase Activity RNA Methyltransferase Activity Transferase Activity Identical Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	RRNA 2'-O-methylation RRNA Processing RNA Processing Methylation
Pathways		rRNA modification in the mitochondrion
Drugs
Diseases
GWAS
Novel Interacting Genes		16 novel interacting genes: AIG1 APP ARLN BTN2A2 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP OGT SCARF1 SHANK3 TNF UBIAD1 ZFPL1
Interacting Genes		16 interacting genes: AIG1 APP ARLN BTN2A2 FBXO7 FHL3 GAD2 GALNT2 JAGN1 MIP OGT SCARF1 SHANK3 TNF UBIAD1 ZFPL1
Entrez ID		55178
HPRD ID		15266
Ensembl ID		ENSG00000171861
Uniprot IDs		Q9HC36
PDB IDs		7OI6
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Amyloid-beta Complex Negative Regulation Of Blood Circulation Growth Cone Lamellipodium Neuron Projection Organization Positive Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of MiRNA Transcription Regulation Of Synapse Organization Membrane Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Positive Regulation Of Excitatory Postsynaptic Potential Amylin Binding Neuron Maturation Positive Regulation Of Toll Signaling Pathway Regulation Of Long-term Synaptic Potentiation Regulation Of Amyloid-beta Clearance Positive Regulation Of Long-term Synaptic Potentiation Astrocyte Activation Positive Regulation Of Synaptic Transmission Positive Regulation Of Developmental Process Positive Regulation Of Membrane Protein Ectodomain Proteolysis Dendrite Development Microglial Cell Activation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Regulation Of Nervous System Process Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Membrane Protein Ectodomain Proteolysis Neuron Remodeling Regulation Of Generation Of Precursor Metabolites And Energy Leukocyte Activation Involved In Inflammatory Response Negative Regulation Of Bile Acid Secretion Positive Regulation Of Translational Initiation By Iron Positive Regulation Of Interleukin-33 Production Response To Gram-negative Bacterium Positive Regulation Of Translational Initiation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Branching Involved In Lung Morphogenesis Response To Monosaccharide Response To Carbohydrate Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Vitamin K Biosynthetic Process Menaquinone Biosynthetic Process Modulation Of Excitatory Postsynaptic Potential Cellular Response To Amyloid-beta
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