PPP1R10

Description		protein phosphatase 1 regulatory subunit 10
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Chromatin Nucleus Nucleoplasm Chromosome Nuclear Body PTW/PP1 Phosphatase Complex
	Molecular Function	DNA Binding RNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Zinc Ion Binding Protein Phosphatase Regulator Activity Metal Ion Binding Enzyme-substrate Adaptor Activity
	Biological Process	RNA Polymerase II Promoter Clearance Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II Protein Import Into Nucleus Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Telomere Maintenance Positive Regulation Of Transcription Elongation By RNA Polymerase II Negative Regulation Of Transcription Elongation By RNA Polymerase II Protein Stabilization Negative Regulation Of Mitotic DNA Damage Checkpoint Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular volume ( 27863252) Schizophrenia ( 30285260)
Novel Interacting Genes		7 novel interacting genes: APP HNRNPK MDM2 PPP1CA PRKACA UBC WDR82
Interacting Genes		7 interacting genes: APP HNRNPK MDM2 PPP1CA PRKACA UBC WDR82
Entrez ID		5514
HPRD ID		04797
Ensembl ID		ENSG00000204569
Uniprot IDs		Q2L6I0 Q96QC0
PDB IDs		6ZV2 8SW5
Enriched GO Terms of Interacting Partners?		Regulation Of Carbohydrate Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Promoter Clearance PTW/PP1 Phosphatase Complex Regulation Of Apoptotic Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Response To Lead Ion Negative Regulation Of Macromolecule Biosynthetic Process Transition Metal Ion Binding Positive Regulation Of Small Molecule Metabolic Process Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription, Elongation Amyloid Fibril Formation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Postsynaptic Modulation Of Chemical Synaptic Transmission Protein Domain Specific Binding Postsynapse Positive Regulation Of Biosynthetic Process Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Metabolic Process Regulation Of Blood Circulation Positive Regulation Of Protein Transport Ribonucleoprotein Complex Binding Regulation Of Protein Export From Nucleus Macromolecule Metabolic Process Positive Regulation Of Glucose Metabolic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Metal Ion Response To Light Stimulus Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Calcium-mediated Signaling Regulation Of Glycolytic Process Regulation Of Small Molecule Metabolic Process Regulation Of Endocytosis Ubiquitin Protein Ligase Binding Regulation Of Protein Processing Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of Nucleocytoplasmic Transport Regulation Of Protein Maturation Positive Regulation Of DNA-templated Transcription, Elongation Amyloid-beta Complex Positive Regulation Of Metabolic Process Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion
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