DYNC2I1

Description		dynein 2 intermediate chain 1
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GO Annotations	Cellular Component	Pericentriolar Material Spindle Pole Extracellular Space Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Cilium Interphase Microtubule Organizing Center Ciliary Basal Body Cell Projection Ciliary Tip Ciliary Base
	Molecular Function	Protein Binding Dynein Light Chain Binding Dynein Heavy Chain Binding
	Biological Process	Cell Projection Organization Intraciliary Retrograde Transport Intraciliary Transport Embryonic Skeletal System Morphogenesis Cilium Assembly
Pathways		Intraflagellar transport
Drugs
Diseases
GWAS
Novel Interacting Genes		3 novel interacting genes: HMGB1 NRIP1 TK1
Interacting Genes		3 interacting genes: HMGB1 NRIP1 TK1
Entrez ID		55112
HPRD ID		08545
Ensembl ID		ENSG00000126870
Uniprot IDs		A0A140VK66 Q8WVS4
PDB IDs		6RLB 6SC2 8RGG 8RGH
Enriched GO Terms of Interacting Partners?		Transcription Corepressor Activity Regulation Of Mismatch Repair Negative Regulation Of DNA-templated Transcription Initiation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex Positive Regulation Of Hematopoietic Progenitor Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Positive Regulation Of Toll-like Receptor 2 Signaling Pathway T-helper 1 Cell Activation Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Positive Regulation Of Toll-like Receptor 9 Signaling Pathway Myeloid Progenitor Cell Differentiation Negative Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Supercoiled DNA Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Dendritic Cell Differentiation Regulation Of Endodeoxyribonuclease Activity Negative Regulation Of Apoptotic Cell Clearance Transcription Coactivator Activity Neutrophil Clearance DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Thymidine Biosynthetic Process Thymidine Kinase Activity Ovarian Follicle Rupture DNA Geometric Change Regulation Of Glycogen Catabolic Process Bubble DNA Binding Deoxyribonucleoside Monophosphate Biosynthetic Process Regulation Of Apoptotic Cell Clearance DNA Topological Change Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Toll-like Receptor 9 Signaling Pathway Endothelial Cell Chemotaxis RAGE Receptor Binding Cellular Response To Lipid Regulation Of T Cell Mediated Immune Response To Tumor Cell T-helper 1 Cell Differentiation DNA Binding, Bending Cellular Response To Interleukin-7 Response To Interleukin-7 Positive Regulation Of Monocyte Chemotactic Protein-1 Production Regulation Of Dendritic Cell Differentiation Positive Regulation Of Viral Entry Into Host Cell Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
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