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SPDL1

Description spindle apparatus coiled-coil protein 1
Image
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Kinetochore
  • Spindle Pole
  • Outer Kinetochore
  • Nucleus
  • Chromosome
  • Cytoplasm
  • Centrosome
  • Cytosol
  • Cytoskeleton
Molecular Function
  • Protein Binding
  • Enzyme Binding
  • Kinetochore Binding
Biological Process
  • Establishment Of Mitotic Spindle Orientation
  • Mitotic Metaphase Chromosome Alignment
  • Mitotic Spindle Assembly Checkpoint Signaling
  • Cell Migration
  • Protein Localization To Kinetochore
  • Cell Division
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Bipolar disorder x sex interaction ( 34099189)
Novel Interacting Genes 10 novel interacting genes: CA8 CEP126 DNAAF4 GPS2 ITSN1 PPP1R18 RTP5 TRAF4 USP15 USP45
Interacting Genes 10 interacting genes: CA8 CEP126 DNAAF4 GPS2 ITSN1 PPP1R18 RTP5 TRAF4 USP15 USP45
Entrez ID 54908
HPRD ID 08623
Ensembl ID ENSG00000040275
Uniprot IDs Q96EA4
PDB IDs 8ARF
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025