LAX1

Description		lymphocyte transmembrane adaptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Cytosol Plasma Membrane Membrane Membrane Raft
	Molecular Function	Protein Binding Protein Kinase Binding SH2 Domain Binding
	Biological Process	Adaptive Immune Response Immune System Process Immune Response Intracellular Signal Transduction B Cell Activation Negative Regulation Of MAPK Cascade Lymphocyte Activation Antigen Receptor-mediated Signaling Pathway Negative Regulation Of T Cell Activation Regulation Of Lymphocyte Activation
Pathways
Drugs
Diseases
GWAS		Malaria ( 31844061) Male-pattern baldness ( 28196072)
Novel Interacting Genes		9 novel interacting genes: GRAP2 GRB2 GRB7 IDH1 LCK NDN STAMBPL1 SYK ZAP70
Interacting Genes		9 interacting genes: GRAP2 GRB2 GRB7 IDH1 LCK NDN STAMBPL1 SYK ZAP70
Entrez ID		54900
HPRD ID		08312
Ensembl ID		ENSG00000122188
Uniprot IDs		Q8IWV1
PDB IDs
Enriched GO Terms of Interacting Partners?		Phosphotyrosine Residue Binding Antigen Receptor-mediated Signaling Pathway Beta Selection Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Non-membrane Spanning Protein Tyrosine Kinase Activity B Cell Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Immune Response-activating Cell Surface Receptor Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of MAPK Cascade Positive Regulation Of Gamma-delta T Cell Differentiation T Cell Activation Positive Regulation Of Gamma-delta T Cell Activation Gamma-delta T Cell Differentiation Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Immune Response-activating Signaling Pathway Regulation Of Leukocyte Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cytosol Positive Regulation Of T Cell Differentiation Protein Tyrosine Kinase Activity Immune Response-regulating Signaling Pathway Activation Of Immune Response Positive Regulation Of Lymphocyte Differentiation T Cell Receptor Complex Gamma-delta T Cell Activation Phospholipase Binding Protein Kinase Binding Lymphocyte Activation T Cell Differentiation Positive Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation T Cell Selection Regulation Of T Cell Differentiation Positive Regulation Of Leukocyte Differentiation Leukocyte Activation Regulation Of Signal Transduction Cell-cell Junction Fc-gamma Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Lymphocyte Differentiation
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