DNAJB12

Description		DnaJ heat shock protein family (Hsp40) member B12
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GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane
	Molecular Function	Hsp70 Protein Binding
	Biological Process	Protein Folding ERAD Pathway Protein-containing Complex Assembly Cellular Response To Misfolded Protein
Pathways
Drugs
Diseases
GWAS		Refractive error ( 32231278) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Novel Interacting Genes		2 novel interacting genes: CCR1 FBXO7
Interacting Genes		2 interacting genes: CCR1 FBXO7
Entrez ID		54788
HPRD ID		07086
Ensembl ID		ENSG00000148719
Uniprot IDs		J3KPS0 Q9NXW2
PDB IDs		2CTP
Enriched GO Terms of Interacting Partners?		Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Chemokine (C-C Motif) Ligand 5 Binding Chemokine (C-C Motif) Ligand 7 Binding Lewy Body Core Regulation Of Hemopoiesis Chemokine Receptor Activity Positive Regulation Of Osteoclast Differentiation Negative Regulation Of Developmental Process Positive Regulation Of Monocyte Chemotaxis Positive Regulation Of Neuroinflammatory Response Dendritic Cell Migration Dendritic Cell Chemotaxis Negative Regulation Of Biomineral Tissue Development Monocyte Chemotaxis Regulation Of Cell Development Negative Regulation Of Bone Mineralization C-C Chemokine Binding C-C Chemokine Receptor Activity Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Positive Regulation Of Autophagy Of Mitochondrion Protein Targeting To Mitochondrion Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Locomotion Regulation Of Monocyte Chemotaxis Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Neuroinflammatory Response Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Ossification Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitophagy Regulation Of Autophagy Of Mitochondrion G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Multicellular Organismal Development Positive Regulation Of Myeloid Leukocyte Differentiation Canonical NF-kappaB Signal Transduction Negative Regulation Of Lymphocyte Differentiation SCF Ubiquitin Ligase Complex Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Osteoclast Differentiation Regulation Of Immune System Process Regulation Of Cell Differentiation Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Cell Cycle G1/S Phase Transition
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