CROT

Description		carnitine O-octanoyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding Carnitine O-octanoyltransferase Activity Transferase Activity Acyltransferase Activity
	Biological Process	Generation Of Precursor Metabolites And Energy Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Beta-oxidation Carnitine Metabolic Process Fatty Acid Transport Coenzyme A Metabolic Process Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase Medium-chain Fatty Acid Metabolic Process
Pathways		Beta-oxidation of pristanoyl-CoA Peroxisomal protein import Peroxisomal protein import
Drugs		Levocarnitine (3-Carboxy-2-(R)-Hydroxy-Propyl)-Trimethyl-Ammonium 3-Carboxy-N,N,N-Trimethyl-2-(Octanoyloxy)Propan-1-Aminium
Diseases
GWAS		Blood protein levels ( 30072576) Lung cancer ( 28604730)
Novel Interacting Genes		1 novel interacting genes: PEX5
Interacting Genes		1 interacting genes: PEX5
Entrez ID		54677
HPRD ID		12081
Ensembl ID		ENSG00000005469
Uniprot IDs		Q9UKG9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Import Into Peroxisome Matrix, Translocation Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Protein Import Into Peroxisome Matrix, Docking Protein Import Into Peroxisome Membrane Protein Import Into Peroxisome Matrix, Substrate Release Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix, Receptor Recycling Protein Carrier Chaperone Protein Unfolding Protein Import Into Peroxisome Matrix Pexophagy Peroxisomal Membrane Transport Establishment Of Protein Localization To Peroxisome Cerebral Cortex Neuron Differentiation Receptor Recycling Peroxisome Organization Intracellular Protein Transmembrane Transport Cerebral Cortex Cell Migration Positive Regulation Of Multicellular Organism Growth Very Long-chain Fatty Acid Metabolic Process Forebrain Neuron Differentiation Telencephalon Cell Migration Forebrain Cell Migration Receptor Metabolic Process Peroxisomal Matrix Fatty Acid Beta-oxidation Protein Monoubiquitination Endoplasmic Reticulum Organization Peroxisomal Membrane Regulation Of Multicellular Organism Growth Protein Transmembrane Transport Fatty Acid Oxidation Fatty Acid Catabolic Process Lipid Oxidation Protein Tetramerization Cellular Response To Reactive Oxygen Species Neuromuscular Process Mitochondrial Membrane Organization Peroxisome Lipid Modification Central Nervous System Neuron Differentiation Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Neuron Migration Macroautophagy Positive Regulation Of Developmental Growth Response To Reactive Oxygen Species Establishment Of Protein Localization To Membrane
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