PPA1

Description		inorganic pyrophosphatase 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Magnesium Ion Binding Inorganic Diphosphate Phosphatase Activity Pyrophosphatase Activity Hydrolase Activity Metal Ion Binding
	Biological Process	Phosphate-containing Compound Metabolic Process
Pathways		Cytosolic tRNA aminoacylation Pyrophosphate hydrolysis
Drugs
Diseases
GWAS
Novel Interacting Genes		11 novel interacting genes: CEBPA ERBB2 HSPB1 MCPH1 MTRNR2L1 SETDB1 SUMO4 TP53 UBC UNC119 WIPI1
Interacting Genes		11 interacting genes: CEBPA ERBB2 HSPB1 MCPH1 MTRNR2L1 SETDB1 SUMO4 TP53 UBC UNC119 WIPI1
Entrez ID		5464
HPRD ID		01527
Ensembl ID		ENSG00000180817
Uniprot IDs		Q15181 V9HWB5
PDB IDs		6C45 7BTN 7CMO 8J7Q
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Stem Cell Proliferation Negative Regulation Of Stem Cell Proliferation Regulation Of Stem Cell Proliferation RNA Polymerase II-specific DNA-binding Transcription Factor Binding Cellular Response To Xenobiotic Stimulus Regulation Of DNA-templated Transcription Initiation Generation Of Precursor Metabolites And Energy RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Protein Heterodimerization Activity Negative Regulation Of Cell Development Response To Vitamin B2 Regulation Of Metabolic Process C/EBP Complex Regulation Of Protein Metabolic Process RNA Polymerase I Core Binding Protein Localization To Synapse Regulation Of Phosphorus Metabolic Process ERBB3:ERBB2 Complex Intracellular Protein Localization Regulation Of Protein Phosphorylation Protein Localization To Cell Junction T Cell Proliferation Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Receptor Tyrosine Kinase Binding Endosome Membrane Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Regulation Of Autophagy Cytoskeleton Oligodendrocyte Apoptotic Process Negative Regulation Of Fermentation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Promoter-specific Chromatin Binding Negative Regulation Of Pentose-phosphate Shunt Negative Regulation Of Helicase Activity Oxidative Stress-induced Premature Senescence Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate Autophagy Of Mitochondrion Negative Regulation Of G1 To G0 Transition Glucose Catabolic Process To Lactate Via Pyruvate Germ Cell Nucleus Cellular Response To Actinomycin D Protein Tag Activity Negative Regulation Of Caveolin-mediated Endocytosis Vesicle Targeting, Trans-Golgi To Endosome Chromatin Binding Negative Regulation Of Hemopoiesis
Tagcloud ?