SSH1

Description		slingshot protein phosphatase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Lamellipodium Growth Cone Midbody Cell Leading Edge Cleavage Furrow Cell Projection Synapse
	Molecular Function	Actin Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Protein Binding Hydrolase Activity Phosphatase Activity
	Biological Process	Cell Morphogenesis Protein Dephosphorylation Actin Cytoskeleton Organization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Synaptic Plasticity Regulation Of Protein Metabolic Process Cellular Response To ATP Excitatory Chemical Synaptic Transmission Positive Regulation Of AMPA Glutamate Receptor Clustering Positive Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Excitatory Postsynaptic Potential
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean platelet volume ( 27863252) Platelet count ( 32888494)
Novel Interacting Genes		6 novel interacting genes: ACTB AKT1 CFL1 CFL2 CORO1B DSTN
Interacting Genes		6 interacting genes: ACTB AKT1 CFL1 CFL2 CORO1B DSTN
Entrez ID		54434
HPRD ID		09486
Ensembl ID		ENSG00000084112
Uniprot IDs		Q8WYL5
PDB IDs
Enriched GO Terms of Interacting Partners?		Actin Filament Fragmentation Actin Filament Depolymerization Positive Regulation Of Actin Filament Depolymerization Actin Filament Severing Positive Regulation Of Protein Depolymerization Actin Filament-based Process Regulation Of Organelle Organization Positive Regulation Of Protein-containing Complex Disassembly Protein Depolymerization Glutamatergic Synapse Lamellipodium Actin Filament Binding Regulation Of Actin Filament Depolymerization Actin Polymerization Or Depolymerization Actin Filament Organization Regulation Of Actin Filament Organization Actin Cytoskeleton Regulation Of Actin Cytoskeleton Organization Nitric-oxide Synthase Regulator Activity Actin Cytoskeleton Organization Regulation Of Protein Depolymerization Actin Binding Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament-based Process Cell Motility Cellular Response To Ether Positive Regulation Of Cellular Component Organization Regulation Of Protein-containing Complex Disassembly Nuclear Matrix Regulation Of Cellular Component Organization Supramolecular Fiber Organization Positive Regulation Of Organelle Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Protein-containing Complex Disassembly Regulation Of Cytoskeleton Organization Positive Regulation Of Supramolecular Fiber Organization Vesicle Response To Ether Positive Regulation Of Cytoskeleton Organization Cell-cell Junction Positive Regulation Of Lamellipodium Organization Regulation Of Cellular Component Size Cellular Response To Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Response To Growth Factor Extracellular Exosome Regulation Of Lamellipodium Organization Response To Epidermal Growth Factor Cytoskeleton Organization
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