SEPTIN4

Description		septin 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Cilium Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Transport Vesicle Axon Dendrite Septin Complex Cytoplasmic Vesicle Motile Cilium Cell Division Site Cell Projection Perikaryon Synapse Sperm Annulus Dopaminergic Synapse Presynapse
	Molecular Function	Nucleotide Binding Magnesium Ion Binding GTPase Activity Structural Molecule Activity Protein Binding GTP Binding Identical Protein Binding Molecular Adaptor Activity
	Biological Process	Neuron Migration Apoptotic Process Spermatogenesis Intracellular Protein Localization Regulation Of Exocytosis Cell Differentiation Flagellated Sperm Motility Positive Regulation Of Protein Ubiquitination Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Spermatid Differentiation Cell Division Hematopoietic Stem Cell Homeostasis Cytoskeleton-dependent Cytokinesis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Novel Interacting Genes		10 novel interacting genes: AREL1 BCL2 PRKN SEPTIN5 SEPTIN8 SNCA SNCAIP SNCB TSC2 XIAP
Interacting Genes		10 interacting genes: AREL1 BCL2 PRKN SEPTIN5 SEPTIN8 SNCA SNCAIP SNCB TSC2 XIAP
Entrez ID		5414
HPRD ID		04738
Ensembl ID		ENSG00000108387
Uniprot IDs		J3KSZ7 O43236
PDB IDs		6WB3
Enriched GO Terms of Interacting Partners?		Phenol-containing Compound Metabolic Process Dopamine Metabolic Process Catecholamine Metabolic Process Biogenic Amine Metabolic Process Amine Metabolic Process Regulation Of Neurotransmitter Secretion Cell Death Positive Regulation Of Protein Linear Polyubiquitination Neuron Apoptotic Process Synaptic Vesicle Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Apoptotic Process Molecular Adaptor Activity Apoptotic Process Negative Regulation Of Programmed Cell Death Programmed Cell Death Dopamine Uptake Involved In Synaptic Transmission Regulation Of Transport Regulation Of Neuron Apoptotic Process Cuprous Ion Binding Protein Polyubiquitination Catecholamine Uptake Dopamine Uptake Septin Ring Septin Complex Negative Regulation Of Autophagy Cell Division Site Synaptic Transmission, Dopaminergic Regulation Of SNARE Complex Assembly Neuronal Cell Body Regulation Of Protein Stability Regulation Of Autophagy Positive Regulation Of Protein Polyubiquitination Regulation Of Apoptotic Process Dopamine Transport Neurotransmitter Reuptake Synaptic Vesicle Membrane Regulation Of Neurotransmitter Uptake Regulation Of Dopamine Metabolic Process Inclusion Body Regulation Of Programmed Cell Death Phospholipase Binding Adult Behavior Regulation Of Dopamine Secretion Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Synapse Regulation Of Protein Polyubiquitination Modulation Of Chemical Synaptic Transmission Monoamine Transport Amyloid Fibril Formation
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