FGFRL1

Description		fibroblast growth factor receptor like 1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Membrane Transport Vesicle Cell-cell Contact Zone
	Molecular Function	Fibroblast Growth Factor Receptor Activity Heparin Binding Fibroblast Growth Factor Binding Identical Protein Binding
	Biological Process	Skeletal System Development Heart Valve Morphogenesis Negative Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Ventricular Septum Morphogenesis Diaphragm Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		FGFRL1 modulation of FGFR1 signaling
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bone mineral density ( 24249740) Femoral neck bone mineral density ( 29499414) Fractures ( 30598549 30158200) Heel bone mineral density ( 28869591 30598549) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Obesity-related traits ( 23251661) Occipital lobe volume ( 31396565) Primary biliary cholangitis ( 26394269) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Serum alkaline phosphatase levels ( 33547301)
Novel Interacting Genes		1 novel interacting genes: FGF2
Interacting Genes		1 interacting genes: FGF2
Entrez ID		53834
HPRD ID		16163
Ensembl ID		ENSG00000127418
Uniprot IDs		A0PJ49 Q8N441
PDB IDs
Enriched GO Terms of Interacting Partners?		Growth Factor Dependent Regulation Of Skeletal Muscle Satellite Cell Proliferation Response To Wortmannin Positive Regulation Of Inner Ear Receptor Cell Differentiation Positive Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Angiogenesis Involved In Coronary Vascular Morphogenesis Regulation Of Retinal Cell Programmed Cell Death Lymphatic Endothelial Cell Migration Positive Regulation Of Cell Fate Specification Positive Regulation Of Lens Fiber Cell Differentiation Positive Regulation Of Inner Ear Auditory Receptor Cell Differentiation Corticotropin Hormone Secreting Cell Differentiation Chemokine Binding Receptor-receptor Interaction Thyroid-stimulating Hormone-secreting Cell Differentiation Regulation Of Inner Ear Auditory Receptor Cell Differentiation Regulation Of Lens Fiber Cell Differentiation Chondroblast Differentiation Cerebellar Granule Cell Precursor Proliferation Positive Regulation Of Neuroepithelial Cell Differentiation Positive Regulation Of Blood Vessel Branching Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Cell Proliferation In External Granule Layer Behavioral Response To Ethanol Regulation Of Blood Vessel Branching Positive Regulation Of Cerebellar Granule Cell Precursor Proliferation Paracrine Signaling Positive Regulation Of Epithelial Tube Formation Negative Regulation Of Fibroblast Migration Regulation Of Skeletal Muscle Satellite Cell Proliferation Hyaluronan Catabolic Process Positive Regulation Of Cell Fate Commitment Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Endothelial Cell Chemotaxis Regulation Of Skeletal Muscle Cell Proliferation Mammary Gland Epithelial Cell Differentiation Inner Ear Auditory Receptor Cell Differentiation Histone H3K9me2/3 Reader Activity Inner Ear Receptor Cell Differentiation Organ Induction Fibroblast Growth Factor Receptor Binding Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cell Fate Specification Hyaluronan Metabolic Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Neuroendocrine Cell Differentiation Glycosaminoglycan Catabolic Process Positive Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Stem Cell Proliferation
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