PLIN1

Description		perilipin 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lipid Droplet Cytosol
	Molecular Function	Protein Binding Lipid Binding
	Biological Process	Lipid Metabolic Process Lipid Catabolic Process Cellular Response To Cold
Pathways		Triglyceride catabolism Transcriptional regulation of white adipocyte differentiation NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		HDL cholesterol ( 30275531)
Novel Interacting Genes		4 novel interacting genes: ABHD5 BSCL2 LIPE PRKACA
Interacting Genes		4 interacting genes: ABHD5 BSCL2 LIPE PRKACA
Entrez ID		5346
HPRD ID		01364
Ensembl ID		ENSG00000166819
Uniprot IDs		O60240
PDB IDs
Enriched GO Terms of Interacting Partners?		Lipid Droplet Triacylglycerol Lipase Activity Regulation Of Lipid Metabolic Process Regulation Of Lipid Catabolic Process Lipid Metabolic Process Sterol Ester Esterase Activity Diacylglycerol Lipase Activity All-trans-retinyl-palmitate Hydrolase, All-trans-retinol Forming Activity Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Protein Localization To Lipid Droplet Positive Regulation Of Lipid Metabolic Process Negative Regulation Of Triglyceride Storage Lipase Activator Activity Retinyl-palmitate Esterase Activity Lipid Catabolic Process Diacylglycerol Catabolic Process CAMP-dependent Protein Kinase Activity Monoacylglycerol Lipase Activity Phosphate-containing Compound Metabolic Process Glycerolipid Metabolic Process Protein Phosphorylation CAMP-dependent Protein Kinase Complex Cellular Response To Parathyroid Hormone Stimulus Cellular Response To Glucagon Stimulus High-density Lipoprotein Particle Assembly Mitochondrial Protein Catabolic Process CAMP/PKA Signal Transduction Nucleotide-activated Protein Kinase Complex Channel Activator Activity Vascular Endothelial Cell Response To Laminar Fluid Shear Stress Lysophosphatidic Acid Acyltransferase Activity Positive Regulation Of Triglyceride Catabolic Process Interleukin-2-mediated Signaling Pathway Cellular Response To Epinephrine Stimulus Negative Regulation Of Catabolic Process Phosphorylation Lipase Activity Ether Lipid Metabolic Process Diacylglycerol Metabolic Process Triglyceride Catabolic Process Acylglycerol Catabolic Process Catabolic Process Regulation Of Hormone Levels Protein-lipid Complex Assembly Protein Serine/threonine/tyrosine Kinase Activity Regulation Of Cardiac Conduction Vascular Endothelial Cell Response To Fluid Shear Stress Negative Regulation Of Glycolytic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Interleukin-2 Production
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